Abstract
Cytokeratins and cytokeratin genes in Xenopus laevis have been studied from both a structural and a developmental point of view. The former must be seen in the context of the extensive work on cytokeratins in many vertebrate animals; the information obtained for Xenopus provides additional comparative opportunities with important evolutionary implications. Since most other studies on cytokeratins have been done on mammalian material, it is very useful to have extensive data available on a cold-blooded animal as well. The second major impetus for this work came from developmental considerations: cytokeratins are prominent tissue-specific products and the study of their expression proved to be a powerful tool for the characterization of developmental processes.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bisbee, C. A., Baker, M. A., Wilson, A. C., Hadji-Adzimi, I., and Fischberg, M., 1977, Albumin phylogeny for clawed frogs (Xenopus), Science 195: 785–787.
Dawid, I. B., and Sargent, T. D., 1986, Molecular embryology in amphibians: New approaches to old questions, Trends Genet. 2: 47–50.
Ellison, T. R., Mathisen, P. M., and Miller, L., 1985, Developmental changes in keratin patterns during epidermal maturation, Dev. Biol. 112: 329–337.
Hanukoglu, I., and Fuchs, E., 1983, The cDNA sequence of a type II cytoskeletal keratin reveals constant and variable structural domains among keratins, Cell 33: 915–924.
Hoffmann, W., and Franz, J. K., 1984, Amino acid sequence of the carboxy-terminal part of an acidic type I cytokeratin from Xenopus laevis epidermis as predicted from the cDNA sequence, EMBO J. 3: 1301–1306.
Hoffmann, W., Franz, J. K., and Franke, W. W., 1985, Amino acid microheterogeneity of basic (type II) cytokeratins of Xenopus laevis epidermis and evolutionary conservativity of helical and non-helical domains, J. Mol Biol 184: 713–724.
Jonas, E., Sargent, T. D., and Dawid, I. B., 1985, Epidermal keratin gene expressed in embryos of Xenopus laevis, Proc. Natl Acad. Sci. USA 82: 5413–5417.
Marchuk, D., McCrohon, S., and Fuchs, E., 1984, Remarkable conservation of structure among intermediate filament genes, Cell 39: 491–498.
Nieuwkoop, P. D., and Faber, J., 1967, Normal Table of Xenopus laevis (Daudin), 2nd ed., North-Holland, Amsterdam.
Okada, A., Shin, T., Dworkin-Rastl, E., Dworkin, M., and Zubay, G., 1985, Constancy of DNA organization of polymorphic and nonpolymorphic genes during development in Xenopus, Differentiation 29: 14–19.
Sargent, T. D., and Dawid, I. B., 1983, Differential gene expression in the gastrula of Xenopus laevis, Science 222: 135–139.
Sargent, T. D., Jamrich, M., and Dawid, I. B., 1986, Cell interactions and the control of gene activity during early development in Xenopus laevis, Dev. Biol 114: 238–246.
Steinert, P. M., and Parry, D. A. D., 1986, Intermediate filaments: Conformity and diversity of expression and structure, Annu. Rev. Cell Biol 1: 41–65.
Steinert, P. M., Steven, A. C., and Roop, D. R., 1985, The molecular biology of intermediate filaments, Cell 42: 411–419.
Wahli, W., Dawid, I. B., Ryffel, G. U., and Weber, R., 1981, Vitellogenesis and the vitellogenin gene family, Science 212: 298–304.
Wahli, W., Germond, J.-E., ten Heggeler, B., and May, F. E. B., 1982, Vitellogenin genes A1 and B2 are linked in the Xenopus genome, Proc. Natl Acad. Sci. USA 70: 6832–6836.
Wilbur, W. J., and Lipman, D. J., 1983, Similarity searches of the nucleic acid and protein data banks, Proc. Natl Acad. Sci. USA 80: 726–730.
Winkles, J. A., Jamrich, M., Jonas, E., Kay, B. K., Miyatani, S., Sargent, T. D., and Dawid, I. B., 1984, Gene expression during embryogenesis in Xenopus laevis, in: Molecular Biology of Development (E. H. Davidson and R. Firtel, eds.), Liss, New York, pp. 93–108.
Winkles, J. A., Sargent, T. D., Parry, D. A. D., Jonas, E., and Dawid, I. B., 1985, Developmentally regulated cytokeratin gene in Xenopus laevis, Mol. Cell Biol. 5: 2575–2581.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer Science+Business Media New York
About this chapter
Cite this chapter
Sargent, T.D. et al. (1990). Keratins and Their Genes in Xenopus laevis. In: Goldman, R.D., Steinert, P.M. (eds) Cellular and Molecular Biology of Intermediate Filaments. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9604-9_12
Download citation
DOI: https://doi.org/10.1007/978-1-4757-9604-9_12
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-9606-3
Online ISBN: 978-1-4757-9604-9
eBook Packages: Springer Book Archive