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Model of Pleuropneumonia in Rats

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Laboratory Aspects of Infections

Part of the book series: Chemotherapy ((CT,volume 2))

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Summary

Intrapleural instillation of a suspension of E. coli (0 25:19:12) results in a double sided pulmonary pleuropneumonial and peribronchial inflammation in albino Wistar rats. This infection lasts at least for 3 weeks when being facilitated by estradiolundecylate (10 mg/rat, weekly) and seems therefore to be a suitable model for testing antimicrobial drugs.

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© 1976 Springer Science+Business Media New York

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Krüger, C., Commichau, R., Henkel, W. (1976). Model of Pleuropneumonia in Rats. In: Williams, J.D., Geddes, A.M. (eds) Laboratory Aspects of Infections. Chemotherapy, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7653-8_39

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  • DOI: https://doi.org/10.1007/978-1-4684-7653-8_39

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7655-2

  • Online ISBN: 978-1-4684-7653-8

  • eBook Packages: Springer Book Archive

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