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Rat Skin Tryptophan 2,3-Dioxygenase

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Kynurenine and Serotonin Pathways

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 294))

Abstract

The fact that a considerable amount of kynurenine (Kyn) is species-specifically accumulated in rat fur was discovered in 1960 by Ishiguro and co-workers (Hotta et al., 1960). The cause of this phenomenon has been exhaustively investigated in our laboratory, but no adequate explanation has been obtained so far.

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References

  • Hotta, K., Ishiguro, I., Naito, J., and Kuzuya, H., 1960, Studies on kynure-nine in rat fur, Seikagaku, 32: 28–31.

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  • Naito, J., Ishiguro, I., Murazumi, T., and Morimoto, M., 1987, Determination of kynurenine in serum by high-performance liquid chromatography after enzymatic conversion to 3-hydroxykynurenine, Anal. Biochem., 161: 16.

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  • Naito, J., Ishiguro, I., Nagamura, Y., and Ogawa, H., 1989, Tryptophan 2, 3-dioxygenase activity in rat skin, Arch. Biochem. Biophys., 270: 236–241.

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© 1991 Plenum Press, New York

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Naito, J., Ishiguro, I., Nagamura, Y., Ogawa, H. (1991). Rat Skin Tryptophan 2,3-Dioxygenase. In: Schwarcz, R., Young, S.N., Brown, R.R. (eds) Kynurenine and Serotonin Pathways. Advances in Experimental Medicine and Biology, vol 294. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5952-4_60

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  • DOI: https://doi.org/10.1007/978-1-4684-5952-4_60

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5954-8

  • Online ISBN: 978-1-4684-5952-4

  • eBook Packages: Springer Book Archive

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