Abstract
Human epidermal Langerhans cells (Lc) play an important role in antigen presentation and immunoregulation in the skin (for review see ref.(1)).They carry antigens and receptors which are identical to those of classical macrophages, i.e. FcIgG, C3 and the MHC class II HLA-D/DR antigens (2,3),but also the T-cell markers CDKT6) and CD4(T4) (4–6). Remarkably, Lc exhibit 50-fold higher amounts of HLA-DR than other cells of the monocyte-macrophage lineage (7).
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Ramirez, G., Braathen, L.R., Kunze, R.O.F., Gelderblom, H. (1988). In Vitro Infection of Human Epidermal Langerhans Cells with HIV. In: Fossum, S., Rolstad, B. (eds) Histophysiology of the Immune System. Advances in Experimental Medicine and Biology, vol 237. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5535-9_135
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