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Structure and Expression of Human Placental Hormone Genes

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Molecular and Cellular Aspects of Reproduction

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 205))

Abstract

One of the important functions of the human placenta is to produce peptide hormones during pregnancy; e.g. human chorionic gonadotropin (hCG) and human placental lactogen (hPL). The appearance of these hormones in maternal serum during pregnancy is quite different. Whereas hCG peaks in the first trimester, hPL reaches maximal levels at term. Since the levels of these hormones differ during the course of gestation, it is apparent that the factors controlling their synthesis are not the same. Thus the human placenta represents a convenient and unique tissue for studying expression of human hormonal genes during development.

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Author information

Authors and Affiliations

  1. Departments of Pharmacology and Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri, 63110, USA

    Irving Boime, Mark Boothby, Robert B. Darnell & Paul Policastro

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  1. Irving Boime
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  2. Mark Boothby
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  3. Robert B. Darnell
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  4. Paul Policastro
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Editor information

Editors and Affiliations

  1. Reproductive Biology Study Section, Division of Research Grants, National Institutes of Health, Westwood Building, Room 307, 20205, Bethesda, Maryland, USA

    Dharam S. Dhindsa D.V.M., Ph.D. (Executive Secretary/Referral Officer) (Executive Secretary/Referral Officer)

  2. Department of Biological Sciences, State University of New York, Cooke Hall 347, 14260, Buffalo, New York, USA

    Om P. Bahl Ph.D. (Professor of Biological Sciences) (Professor of Biological Sciences)

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© 1986 Plenum Press, New York

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Boime, I., Boothby, M., Darnell, R.B., Policastro, P. (1986). Structure and Expression of Human Placental Hormone Genes. In: Dhindsa, D.S., Bahl, O.P. (eds) Molecular and Cellular Aspects of Reproduction. Advances in Experimental Medicine and Biology, vol 205. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5209-9_12

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  • DOI: https://doi.org/10.1007/978-1-4684-5209-9_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5211-2

  • Online ISBN: 978-1-4684-5209-9

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