Behavioral Toxicology

1. Front Matter

   Pages i-xxi

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2. Carbon Monoxide and Human Functions

   • Rodney R. Beard, Netta W. Grandstaff

   Pages 1-27

3. The Effect of Carbon Monoxide on Time Perception, Manual Coordination, Inspection, and Arithmetic

   • Richard D. Stewart, Paul E. Newton, Michael J. Hosko, Jack E. Peterson, James W. Mellender

   Pages 29-60

4. Preliminary Studies of the Effects of Carbon Monoxide on Vigilance in Man

   • J. F. O’Hanlon

   Pages 61-75

5. Carbon Monoxide and Human Performance: A Methodological Exploration

   • Warren H. Teichner

   Pages 77-104

6. The Comparative Effects of Hypoxic and Carbon Monoxide Hypoxia on Behavior

   • Zoltan Annau

   Pages 105-127

7. The Application of a Computer-Controlled Time Discrimination Performance to Problems in Behavioral Toxicology

   • Barry L. Johnson, W. Kent Anger, James V. Setzer, Charles Xintaras

   Pages 129-153

8. Behavioral Toxicity of Anticholinesterase Agents: Methodological, Neurochemical, and Neuropsychological Aspects

   • G. Bignami, N. Rosić, H. Michałek, M. Milošević, G. L. Gatti

   Pages 155-215

9. Behavioral Toxicologic Studies of Dieldrin, DDT, and Ruelene in Sheep

   • Gary A. Van Gelder

   Pages 217-239

10. Use of Behavioral Techniques in the Assessment of Environmental Contaminants

    • George S. Burt

    Pages 241-263

11. Utilities and Limitations of Behavioral Techniques in Industrial Toxicology

    • Timothy O. T. Ts’O, Basil K. J. Leong, Maynard B. Chenoweth

    Pages 265-291

12. Effects of the Inhalation of Cigarette Smoke on Swimming Endurance and Avoidance Behavior in the Rat

    • K. Bättig, P. Driscoll

    Pages 293-309

13. Behavioral Teratology and Toxicology

    • Joan M. Spyker

    Pages 311-349

14. Effects of Drugs on Schedule-Controlled Behavior and Cardiovascular Function in the Squirrel Monkey

    • R. T. Kelleher, W. H. Morse, J. A. Herd

    Pages 351-374

15. Behaviorial, Biochemical, and Morphological Effects of Methamphetamine in the Rhesus Monkey

    • Marian W. Fischman, Charles R. Schuster

    Pages 375-399

16. Behavioral Assessment of Ototoxicity in Nonhuman Primates

    • William C. Stebbins, Sheryl Coombs

    Pages 401-427

17. Quantitative Perspectives on the Long-Term Toxicity of Methylmercury and Similar Poisons

    • Bernard Weiss, William Simon

    Pages 429-437

18. An Overview of Behavioral Toxicology

    • P. B. Dews

    Pages 439-445

19. Back Matter

    Pages 447-469

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Behavioral toxicology is a young discipline in the United States; so young, in fact, that this is one of its first books. Behavioral questions are bound to play a major role in future scientific work and governmental decisions involving the health effects of environmental contaminants and other chemicals. This role springs from two key problems that face scientists and public agencies required to set acceptable exposure standards or to determine criteria for the toxicity of therapeutic chemicals: How do you evaluate effects that may show up only as subtle functional disturbances? And how do you de­ tect toxic effects early enough so that they may still be reversible, before they produce major damage? The contributions in this book come from a collection of scientists whose interests span a wide variety of problem areas. The focus is largely on me­ thodological issues because they represent the most immediate concern of the discipline. We expect that this collection of papers will represent a useful source book for behavioral toxicology for some time. For the past few years, the University of Rochester's Department of Radiation Biology and Biophysics has sponsored a series of international conferences on chemical toxicity, partly as a response to concern over the con­ sequences to health of the rich chemical soup in which we live. This book is based upon presentations made to the fifth of the series. Held in June, 1972, it was the first formal meeting devoted to behavioral toxicology in this country.

• biology
• contaminants
• environment
• environmental contaminants
• health
• health effects
• toxicity
• toxicology
• air pollution and air quality

• Department of Radiation Biology and Biophysics, School of Medicine and Dentistry, University of Rochester, Rochester, USA

  Bernard Weiss, Victor G. Laties

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