Abstract
Over the last decade the treatment of Parkinsonism has under gone major developments. Advances deriving from a logically structured series of laboratory experiments have been transferred to the clinic to generate substantial therapeutic achievements.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Cools, A.R. and Van Rossum, J.M. (1975). Excitation-mediating and inhibition-mediating dopamine-receptors: A new concept towards a better understanding of electrophysiological, biochemical, pharmacological, functional and clinical data. Psychopharma- cologia (Berl). 45 ,243–254.
Cotzias, G.C., Lawrence, W.H., Papavasiliou, P.S., Tolosa, E.S., Mendez, J.S. and Bell-Medura, M. (1976). Treatment of Park inson’s disease with aporphines, possible role of growth hormone. New Engl J. Med 294 ,567–572.
Creese, I.N., Bunt, D.R. and Snyder, S.H. (1976). Dopamine receptor binding; differentiation of agonist and antagonist states with 3H-holaperidol. Life Sci. 17 ,993–1002.
Greenacre, J.K., Coxon, A., Petrie, A. and Reid, J.L. (1976). Comparison of levodopa with carbidopa or benserazide in parkin-sonism. Lancet 2 ,381–384.
Jaton, A.L., Loew, D.M. and Vigouret, J.M. (1975). CF 25–397 (9,10 didehydro-6-methyl-8ß-[2-pyridylthiomethyl] ergoline), anew central dopamine receptor agonist. Proc B.P.S. 56 ,371.
Kartzinel, R. and Calne, D.B. (1976). Studies with bromocriptine Part I. “On-off” phenomena. Neurology, 26 ,508–510.
Kartzinel, R., Perlow, M.J., Carter, A.C., Chase, T.N. and Calne, D.B. (1976). Metabolic studies with bromocriptine in patients with idiopathic Parkinsonism and Huntington’s Chorea. Trans Am Neurol Assoc. In press.
Kartzinel, R., Perlow, M., Teychenne, P., Gielen, A., Gillespie, M., Sadowsky, D. and Calne, D.B. (1976). Bromocriptine and levodopa (with or without carbidopa) in Parkinsonism. Lancet 2 ,272–275.
Libet, B. and Tosaka, T. (1970). Dopamine as a synaptic transmitter and modulator in sympathetic ganglia: A different mode of synaptic action. Proc Nat Acad Sci USA 67 ,667–673.
Lieberman, A., Miyamoto, T., Battista, A. and Goldstein, M. (1975). Studies on the anti-Parkinsonian efficacy of lergotrile. Neurol. 25 ,459–462.
Lloyd, K.G., Davidson, L. and Hornykiewicz, O. (1973). Metabolism of levodopa in the human brain. In Advances in Neurology, Vol. 3, (Calne, D.B., Ed.) pp. 173–188. Raven Press, New York.
Marsden, CD. and Parkes, J.D. (1976). “On-off” effects in patients with Parkinson’s disease on chronic levodopa therapy. Lancet 1 ,292–296.
McLennan, H. and York, D.H. (1967). The action of dopamine on neurons of the caudate nucleus. J. Physiol. (Lond). 189 ,393–402.
Reid, J.L., Calne, D.B., Vakil, S.D., Allen, J.C. and Davies, C.A. (1972). Plasma concentrations of levodopa in Parkinsonism before and after inhibition of peripheral decarboxylase. J. Neurol Sci. 17 ,45–51.
Silbergeld, E.K., Adler, H., Kennedy, S. and Calne, D.B. (1976).Roles of presynaptic dopamine function and hepatic drug metabolism in effects of three dopamine agonists: bromocriptine, lergotrile and CF25-397. In press.
Silbergeld, E.K. and Pfeiffer, R.F. (1976). Differential effects of three dopamine agonists: apomorphine, bromocriptine and lergotrile. In press.
Teychenne, P.F., Jones, A. and Calne, D.B. (1976). Changes in liver function induced by lergotrile. In preparation.
Teychenne, P.F., Pfeiffer, R.F. and Calne, D.B. (1976). Actions of CF25–397 in parkinsonism. In preparation.
Yahr, M.D. (ed.) (1973). In Advances in Neurology, Vol. 2-Treatment of Parkinson’s Disease-the Use of Dopa Deoarboxylase Inhibitors. pp. 303. Raven Press, New York.
Yahr, M.D. (1975). Levodopa. Ann Intern Med. 83 ,667–682.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1977 Plenum Press, New York
About this chapter
Cite this chapter
Calne, D.B., Teychenne, P.F., Pfeiffer, R.F. (1977). Treatment of Parkinsonism. In: Messiha, F.S., Kenny, A.D. (eds) Parkinson’s Disease. Advances in Experimental Medicine and Biology, vol 90. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-2511-6_3
Download citation
DOI: https://doi.org/10.1007/978-1-4684-2511-6_3
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4684-2513-0
Online ISBN: 978-1-4684-2511-6
eBook Packages: Springer Book Archive