Skip to main content
Springer Nature Link
Log in

Coronaviruses

  • Book
  • © 1987

Overview

Editors:
  1. Michael M. C. Lai

    1. University of Southern California School of Medicine, Los Angeles, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Stephen A. Stohlman

    1. University of Southern California School of Medicine, Los Angeles, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 218)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

About this book

Coronaviruses have emerged during the past ten years from being a group of viruses causing a variety of minor veterinary and human diseases to a major virus group of both clinical significance and molecular biological interest. Against this background, two international coronavirus symposia were held in 1980 and 1983. In recent years, the pace of coronavirus research has been quickened even more by infusion of recombinant DNA technology and establishment of various animal model systems to study the pathogenesis and immunology of coronavirus infections. We therefore organized the Third International Coronavirus Symposium held at Asilomar, California in September 1986, which was attended by more than 120 participants representing a cross­ section of both academia and industry. This symposium provided an exciting and stimulating forum for assessing the progress made since the last triennial symposium in Netherlands and to suggest the directions for future efforts. This volume collects the scientific papers presented in this symposium. Three loosely defined areas, Molecular biology, Virus-Cell Interaction and Viral Pathogenesis, are separated. These papers very nicely summarize the current status of coronavirus research. They contain a large amount of sequence data, including the complete sequence of a 27 Kb coronavirus genome, a novel mechanism of mRNA synthesis that is unique to coronviruses, and many exciting aspects of coronavirus pathogenesis and immunology. Reflecting the growing interest in the preparation of vaccines, several papers also address the issues related to coronavirus vaccines, which is an area new to this symposium. Dr.

Similar content being viewed by others

Keywords

Table of contents (74 chapters)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. Coronaviruses: A Historical Perspective

    1. Coronaviruses: A Historical Perspective

      • Leslie P. Weiner
      Pages 1-5

  3. Molecular Biology of Coronaviruses

    1. Molecular Biology of Coronavirus 1986

      • Michael M. C. Lai
      Pages 7-13

    2. The Complete Nucleotide Sequence of Avian Infectious Bronchitis Virus: Analysis of the Polymerase-Coding Region

      • M. E. G. Boursnell, T. D. K. Brown, I. J. Foulds, P. F. Green, F. M. Tomley, M. M. Binns
      Pages 15-29

    3. Sequence and Structure of the Coronavirus Peplomer Protein

      • R. J. de Groot, J. A. Lenstra, W. Luytjes, H. G. M. Niesters, M. C. Horzinek, B. A. M. van der Zeijst et al.
      Pages 31-38

    4. Identification of the Coronavirus MHV-JHM mRNA 4 Gene Product Using Fusion Protein Antisera

      • Dora Ebner, Stuart Siddell
      Pages 39-45

    5. Identification of a New Gene Product Encoded by mRNA D of Infectious Bronchitis Virus

      • A. R. Smith, M. E. G. Boursnell, M. M. Binns, T. D. K. Brown, S. C. Inglis
      Pages 47-54

    6. Expression of Porcine Transmissible Gastroenteritis Virus Genes in E. Coli as β-Galactosidase Chimaeric Proteins

      • Paul Britton, David J. Garwes, Kevin Page, Jean Walmsley
      Pages 55-64

    7. Sequences Involved in the Replication of Coronaviruses

      • P. J. Bredenbeek, J. Charite, J. F. A. Noten, W. Luytjes, M. C. Horzinek, B. A. M. van der Zeijst et al.
      Pages 65-72

    8. Murine Coronavirus 5′-End Genomic RNA Sequence Reveals Mechanism of Leader-Primed Transcription

      • Lisa H. Soe, Chien-Kou Shieh, Shinji Makino, Ming-Fu Chang, Stephen A. Stohlman, Michael M. C. Lai
      Pages 73-81

    9. Expression of the E1 Gene of Mouse Hepatitis Virus (MHV A59) In Vivo and In Vitro

      • Heiner Niemann, Thomas Mayer, Manfred Wirth, Teruko Tamura
      Pages 83-97

    10. RNA Recombination of Coronavirus

      • James G. Keck, Shinji Makino, Lisa H. Soe, John O. Fleming, Stephen A. Stohlman, Michael M. C. Lai
      Pages 99-107

    11. Surface Glycoproteins of Transmissible Gastroenteritis Virus: Functions and Gene Sequence

      • Denis Rasschaert, Bernard Delmas, Bernard Charley, Jeanne Grosclaude, Jacqueline Gelfi, Hubert Laude
      Pages 109-116

    12. Nucleotide Sequence of the Porcine Transmissible Gastroenteritis Coronavirus Matrix Protein Gene

      • Paul A. Kapke, Frank Y. C. Tung, David A. Brian, Roger D. Woods, Ronald Wesley
      Pages 117-122

    13. Deduced Amino Acid Sequence and Potential O-Glycosylation Sites for the Bovine Coronavirus Matrix Protein

      • William Lapps, Brenda G. Hogue, David A. Brian
      Pages 123-129

    14. Glycosylation of the Bovine Coronavirus Hemagglutinin Protein

      • Brenda G. Hogue, David A. Brian
      Pages 131-136

    15. Studies into the Mechanism of MHV Transcription

      • Ralph S. Baric, Chien Kou Shieh, Stephen A. Stohlman, Michael M. C. Lai
      Pages 137-149

    16. Expression of IBV Spike Protein by a Vaccinia Virus Recombinant

      • Fiona Tomley, Matthew Binns, Mike Boursnell, Adrian Mockett
      Pages 151-153

    17. Translation and Processing of MHV-A59 Virion RNA in Reticulocyte Lysates and Infected Cells

      • Mark Denison, Stanley Perlman
      Pages 155-156

    18. Temporal Regulation of RNA Synthesis of Bovine Coronavirus

      • James G. Keck, Brenda G. Hogue, David A. Brian, Michael M. C. Lai
      Pages 157-158
Back to top

Editors and Affiliations

  • University of Southern California School of Medicine, Los Angeles, USA

    Michael M. C. Lai, Stephen A. Stohlman

Bibliographic Information

  • Book Title: Coronaviruses

  • Editors: Michael M. C. Lai, Stephen A. Stohlman

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-1280-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1987

  • Softcover ISBN: 978-1-4684-1282-6Published: 26 April 2012

  • eBook ISBN: 978-1-4684-1280-2Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XII, 591

  • Topics: Medical Microbiology

Publish with us

Policies and ethics

Back to top