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Hemoprotozoan Infections of Domestic Animals: Trypanosomiasis, Babesiosis, Theileriosis, and Anaplasmosis

  • Chapter
Chemotherapy of Parasitic Diseases

Abstract

Arthropod-transmitted hemoparasitic diseases, caused by Trypanosoma, Babesia, Theileria, and Anaplasma, occur throughout the world but are frequently of greatest importance in the tropics and subtropics, where conditions are favorable to the maintenance of vector populations. Vector control and chemotherapy are the primary defenses against these disease agents. Vaccines that prevent these infections have yet to be developed. The attenuated or live vaccines described for anaplasmosis, babesiosis, and theileriosis often depend on specific therapy to reduce the severity of infection while allowing the development of a premunizing immunity (Kuttler, 1979; Todorovic, 1974; Radley, 1981). Chemotherapy, chemoimmunization, and chemoprophylaxis thus comtinue to play an important role in hemoparasitic disease management and prevention. Even so, chemotherapy is not without problems; drug-resistant microorganisms arise, drug residues in tissues of food animals may be detected and prompt removal of the drug from its approved status, and the cost of drugs may be too high for use by poor farmers. The expense and difficulty in developing new replacement compounds for those no longer used for one reason or another are also a serious problem in the world today.

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Authors and Affiliations

  1. U.S. Department of Agriculture, Agricultural Research Service, Hemoparasitic Diseases Research Unit, Washington State University, Pullman, Washington, 99164, USA

    Kenneth L. Kuttler

  2. Department of Microbiology, Ohio State University, Columbus, Ohio, 43210, USA

    Julius P. Kreier

Authors
  1. Kenneth L. Kuttler
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  2. Julius P. Kreier
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Editors and Affiliations

  1. Merck Institute for Therapeutic Research, Rahway, New Jersey, USA

    William C. Campbell

  2. Merck Sharp & Dohme Research Laboratories, Rahway, New Jersey, USA

    Robert S. Rew

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© 1986 Plenum Press, New York

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Kuttler, K.L., Kreier, J.P. (1986). Hemoprotozoan Infections of Domestic Animals: Trypanosomiasis, Babesiosis, Theileriosis, and Anaplasmosis. In: Campbell, W.C., Rew, R.S. (eds) Chemotherapy of Parasitic Diseases. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1233-8_8

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  • DOI: https://doi.org/10.1007/978-1-4684-1233-8_8

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