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A Double Blind Placebo Controlled Trial of Mixed Gangliosides in Diabetic Peripheral and Autonomic Neuropathy

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Ganglioside Structure, Function, and Biomedical Potential

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 174))

Abstract

Diabetic neuropathy is a common complication of diabetes that is incurable at present. The likelihood of clinical manifestations increases with the duration and severity of the hyperglycemia.1–7Apart from the beneficial effects of insulin by continuous infusion8,9 or the alcohol myoinositol, 10–13 the only other drugs tried with questionable benefit in clinical diabetic neuropathy are isaxonine and sorbinil. 15–18

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Author information

Authors and Affiliations

  1. Alexander Simpson Laboratory for Metabolic Research Mint Wing, St. Mary’s Hospital Praed Street, London, W.2., UK

    R. R. Abraham & V. Wynn

  2. Dept. of Neurophysiology, Central Middlesex Hospital, Park Royal, London, W.3., UK

    R. M. Abraham

Authors
  1. R. R. Abraham
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  2. R. M. Abraham
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  3. V. Wynn
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Editor information

Editors and Affiliations

  1. Albert Einstein College of Medicine, Bronx, New York, USA

    Robert W. Ledeen  & Kunihiko Suzuki  & 

  2. Yale University School of Medicine, New Haven, Connecticut, USA

    Robert K. Yu

  3. New York State Psychiatric Institute, New York, New York, USA

    Maurice M. Rapport

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© 1984 Plenum Press, New York

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Abraham, R.R., Abraham, R.M., Wynn, V. (1984). A Double Blind Placebo Controlled Trial of Mixed Gangliosides in Diabetic Peripheral and Autonomic Neuropathy. In: Ledeen, R.W., Yu, R.K., Rapport, M.M., Suzuki, K. (eds) Ganglioside Structure, Function, and Biomedical Potential. Advances in Experimental Medicine and Biology, vol 174. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1200-0_52

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  • DOI: https://doi.org/10.1007/978-1-4684-1200-0_52

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1202-4

  • Online ISBN: 978-1-4684-1200-0

  • eBook Packages: Springer Book Archive

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