Abstract
In order to develop “Intelligent Fluorescence Optical Sensors” (INFOS) for better stability and an improved microprocessor compatibility we have combined the optical sensors, the so-called optodes (1, 2) with integrated excitation source and fluorescence detection device on semiconductor basis. These INFOS can be applied for the analysis of various substances such as oxygen, carbon dioxide, and hydrogen ion activities (3, 4).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
D. W. Lübbers and N. Opitz, Optical fluorescence sensors for continuous measurement of chemical concentrations in biological systems, Sensors and Actuators 4:641–654 (1983).
N. Opitz and D. W. Lübbers, Electrochromic dyes, enzyme reactions and antigen-antibody interactions in fluorescence optic sensor (optode) technology, TALANTA (in press, 1987).
J. L. Gehrich, D. W. Lübbers, N. Opitz, D. R. Hansmann, W. W. Miller, J. K. Tusa and M. Yafuso, Optical fluorescence and its application to an intravascular gas monitoring system. IEEE Trans. Biomed. Eng. 33:117–231 (1986).
D.W. Lübbers, J. Gehrich and N. Opitz, Fiber optics coupled fluorescence sensors for continuous monitoring of blood gases in the extracorporeal circuit, in: “Life Support Systems, Extracorporeal Gas Exchange, Design and Techniques,” A. Lautier, J. P. Gille, eds., Saunders, London (1986), pp. 94–108.
N. Opitz and D. W. Lübbers, Compact CO2 gas analyzer with favourable singnal-to-noise ratio and resolution using special fluorescence sensors (optodes) illuminated by blue LED’s, in: “Oxygen Transport to Tissue VI,” Adv. Exp. Med. & Biol., Vol. 180, D. Bruley, H. I. Bicher, D. Reneau, eds., Plenum Press, New York-London (1984), pp. 757–762.
A. Rademacher, S. Märkle and H. Langhals, Lösliche Perylen-Fluoreszenzfarbstoffe mit hoher Photostabilität, Chem. Ber. 115:2927–2934 (1982).
O. Stern and M. Volmer, Über die Abklingzeit der Fluoreszenz, Z. Phys. 20:183–188 (1919).
N. Opitz and D.W. Lübbers, Increased resolution power in Po2 analysis at lower Po2 levels via sensitivity enhanced optical Po2 sensors (Po2 optodes) using fluorescence dyes, in: “Oxygen Transport to Tissue VI,” Adv. Exp. Med. & Biol., Vol. 180, D. Bruley, H. I. Bicher, D. Reneau, eds., Plenum Press, New York-London, (1984) pp. 261–267.
N. Opitz, Untersuchungen zur Kinetik und Einstellzeit fluoreszenzoptischer Sensoren (Optoden) für die Blutgasanalyse, Biomed. Tech. 30:96–97 (1985).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Plenum Press, New York
About this chapter
Cite this chapter
Opitz, N., Lübbers, D.W. (1988). Blood Gas Analysis Using Fluorescence and Absorption Indicators in Optical Sensors (Optodes) with Integrated Excitation and Fluorescence Detection on Semiconductor Basis. In: Mochizuki, M., Honig, C.R., Koyama, T., Goldstick, T.K., Bruley, D.F. (eds) Oxygen Transport to Tissue X. Advances in Experimental Medicine and Biology, vol 222. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-9510-6_20
Download citation
DOI: https://doi.org/10.1007/978-1-4615-9510-6_20
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4615-9512-0
Online ISBN: 978-1-4615-9510-6
eBook Packages: Springer Book Archive