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A Comparison of the Salient Features of Mouse, Rat, and Human Mammary Tumorigenesis

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Abstract

This chapter briefly discusses the salient features of models of breast carcinogenesis. It is intended not to be an extensive encyclopedia of all models in the literature but to emphasize key features of the main models. The information presented here is very much the authors’ interpretations of selected data in the literature, which, hopefully, will stimulate spirited discussion and new ideas.

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Abbreviations

LDH:

loss of heterozygosity

DCIS:

ductal carcinoma in situ

References

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Medina, D., Thompson, H.J. (2000). A Comparison of the Salient Features of Mouse, Rat, and Human Mammary Tumorigenesis. In: Ip, M.M., Asch, B.B. (eds) Methods in Mammary Gland Biology and Breast Cancer Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4295-7_3

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  • DOI: https://doi.org/10.1007/978-1-4615-4295-7_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6927-1

  • Online ISBN: 978-1-4615-4295-7

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