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Therapeutic Effect of Tribulus Terrestris (Chota Gokhru, an Ayurvedic Drug) in the Management of Experimental Hyperoxaluria

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Urolithiasis 2

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Abstract

Ayurveda is the oldest existing medical system of traditional medicine, having its heritage in ancient India. It is recognized by the World Health Organisation and is still practised. Hyperoxaluria is one of the primary risk factors of urolithiasis. In various systems of traditional medicine, a number of indigenous plants are being used in India and other countries. One such plant is Tribulus terrestris (family zygophyllaceae) common in arid zones of India. Although its extract is known to have diuretic and antilithic properties1 its mode of action is not fully understood. Hence, the present study was undertaken to evaluate the mode of action of T. terrestris in hyperoxaluric rats.

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References

  1. G Santha Kumari and GYN Iyer, Preliminary studies on the diuretic effects of Hygrophila spinosa and Tribulus terrestris, Ind J Med Res 55: 714 (1967).

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  2. H Sidhu, In: Biochemical mechanism of hyperoxaluria and role of urinary inhibitors of calcium oxalate crystallization: “Ph.D. thesis, PGIMER, Chandigarh, India” (1985).

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  3. MSR Murthy, HS Talwar, SK Thind, and R Nath, Effect of sodium glycolate and sodium pyruvate on oxalate synthesizing enzymes in rat liver and kidney, Ann Nutr Metab 27: 355 (1983).

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  4. MR Banner and SB Rosalki, Glyoxylate as a substrate for lactate dehydrogenase, Nature 213: 726 (1967).

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Author information

Authors and Affiliations

  1. Departments of Biochemistry, Postgraduate Institute of Medical Education, Chandigarh, India

    S. K. Thind & R. Nath

  2. Research and Panjab University, Chandigarh, India

    D. Sangeeta & H. Sidhu

Authors
  1. D. Sangeeta
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  2. H. Sidhu
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  3. S. K. Thind
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  4. R. Nath
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Editor information

Editors and Affiliations

  1. Flinders Medical Centre, South Australia, Australia

    Rosemary Ryall  & Villis R. Marshall  & 

  2. Institute of Medical and Veterinary Science, Adelaide, Australia

    Renze Bais  & Allan M. Rofe  & 

  3. Mayo Clinic, Rochester, Minnesota, USA

    Lynwood H. Smith

  4. University of British Columbia, Vancouver, British Columbia, Canada

    Valerie R. Walker

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© 1994 Springer Science+Business Media New York

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Sangeeta, D., Sidhu, H., Thind, S.K., Nath, R. (1994). Therapeutic Effect of Tribulus Terrestris (Chota Gokhru, an Ayurvedic Drug) in the Management of Experimental Hyperoxaluria. In: Ryall, R., Bais, R., Marshall, V.R., Rofe, A.M., Smith, L.H., Walker, V.R. (eds) Urolithiasis 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2556-1_233

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  • DOI: https://doi.org/10.1007/978-1-4615-2556-1_233

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6091-9

  • Online ISBN: 978-1-4615-2556-1

  • eBook Packages: Springer Book Archive

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