Skip to main content

Laser Doppler Perfusion Imaging Compared with Lightguide Laser Doppler Flowmetry, Dynamic Thermographic Imaging and Tissue Spectrophotometry for Investigating Blood Flow in Human Skin

  • Chapter
Oxygen Transport to Tissue XV

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 345))

Abstract

Lightguide laser Doppler flowmetry (LDFc) is widely used both in micro-circulatory research and in clinical blood flow studies (for a review, see Shepherd and Oberg, 1990). Despite the inability to measure blood flow in absolute terms with the method (flux values are quoted in volts), physiological challenges can be used in order to test local and sympathetic control of the microvascular flow (Khan et al., 1991).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abbot, N.C., Swanson Beck J., Carnochan, F.M., Lowe, J.G. and Gibbs, J.H., 1992, Circulatory adaptation to the increased metabolism in skin at the site of the tuberculin reaction, Int. J. Microcirc: Clin. Exp. in press.

    Google Scholar 

  • Beck, J.S. and Spence V.A., 1986, Patterns of blood flow in the microcirculation of the skin during the course of the tuberculin reaction in normal human subjects, Immunology 58:209.

    Google Scholar 

  • Beck, J.S., Gibbs J.H., Potts, R.C., Kardjito, T., Grange, J.M., Jawad E.S. and Spence, V.A., 1989, Histometric studies on biopsies of tuberculin skin test showing evidence of ischaemia and necrosis, J. Pathol. 159:317.

    Article  PubMed  CAS  Google Scholar 

  • Braverman, I.M., Keh, A. and Goldminz, D., 1990, Correlation of laser Doppler wave patterns with underlying microvascular anatomy, J. Invest. Dem:atol. 95:283.

    Article  CAS  Google Scholar 

  • Essex, T.J.H. and Byrne, P.O., 1991, A laser Doppler scanner for imaging blood flow in skin, J. Biomed. Eng. 13:189.

    Article  PubMed  CAS  Google Scholar 

  • Harrison, D.K., Birkenhake, S., Knauf, S.K, Hagen, N., Beier, I. and Kessler, M., 1988, The role of high flow capillary channels in the oxygen supply to skeletal muscle, Adv. Exp. Med Biol. 222:623.

    Article  PubMed  CAS  Google Scholar 

  • Harrison, D.K., Evans, S.D., Abbot, N.C., Swanson Beck, J. and McCollum, P.T., 1992, Spectrophotometric measurements of haemoglobin saturation and concentration in skin during the tuberculin reaction in normal human subjects, Clin. Phys. and Physiol. Meas. in press.

    Google Scholar 

  • Harrison, D.K., Abbot, N.C., Carnochan, F., Swanson Beck, J., James, P.B. and McCollum, P.T., 1993, Protective regulation of oxygen uptake as a result of reduced oxygen extraction during chronic inflammation, Adv. Exp. Med Biol. this volume.

    Google Scholar 

  • Hickman P., Harrison, D.K., Evans, S.D., Belch, J. and McCollum, P.T., 1993, Use of lightguide reflectance spectrophotometry in the assessment of peripheral arterial disease, Adv. Exp. Med. Biol. this volume.

    Google Scholar 

  • Khan, F., Spence, VA., Wilson, S.B. and Abbot, N.C., 1991, Quantification of sympathetic vascular responses in skin by laser Doppler flowmetry, Int. J. Microcirc: Clin. Exp. 10:145.

    CAS  Google Scholar 

  • Shepherd, A.P. and Oberg, PA., 1990, “Laser Doppler Flowmetry,” Kluwer Academic Publishers, Boston.

    Google Scholar 

  • Wardell, K., Jakobsson, A. and Nilsson, G., 1991, Laser imager maps microvascular flow, Diagnost. Imaging Int. March/April:44.

    Google Scholar 

  • Wardell, K., Jakobsson, A. and Nilsson, G., 1992, Laser Doppler perfusion imaging by dynamic light scattering, IEEE Trans. BME, in press.

    Google Scholar 

  • Wilson, S.B. and Spence, VA., 1989, Dynamic thermographie imaging method for quantifying dermal perfusion: potential and limitations, Med. Biol. Eng. Comput. 27:496.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer Science+Business Media New York

About this chapter

Cite this chapter

Harrison, D.K., Abbot, N.C., Beck, J.S., McCollum, P.T. (1994). Laser Doppler Perfusion Imaging Compared with Lightguide Laser Doppler Flowmetry, Dynamic Thermographic Imaging and Tissue Spectrophotometry for Investigating Blood Flow in Human Skin. In: Vaupel, P., Zander, R., Bruley, D.F. (eds) Oxygen Transport to Tissue XV. Advances in Experimental Medicine and Biology, vol 345. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2468-7_112

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-2468-7_112

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6051-3

  • Online ISBN: 978-1-4615-2468-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics