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Encyclopedia of Computational Neuroscience pp 1–6Cite as

Neuropathologies and Networks

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Synonyms

Network disorders

Definition

Brain disorders often coincide with changes in the white and gray matter organization. When we view the gray matter brain regions as nodes of a network, the white matter fiber tracts become the edges. Changes in the nodes or edges of a network can be a sign of brain network disorders. Edge changes might affect spatial features such as the distance between connected nodes or the three-dimensional trajectory of fibers and topological features such as the fiber strength given by the extent of myelination or the thickness of fiber tracts. Such local changes can affect the global modular hierarchical, small-world, or rich-club organization.

Detailed Description

Types of Brain Networks

For brain networks, nodes could be neurons or cortical areas and edges could be axons or fiber tracts. Thus, edges could refer to the structural connectivityof a neural network. Alternatively, edges could signify correlations between the activity patterns of nodes...

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Author information

Authors and Affiliations

  1. School of Computing Science, Newcastle University, Claremont Tower, NE1 7RU, Newcastle-upon-Tyne, Tyne and Wear, UK

    Marcus Kaiser

  2. Institute of Neuroscience, Newcastle University, Newcastle-upon-Tyne, Tyne and Wear, UK

    Marcus Kaiser

Authors
  1. Marcus Kaiser
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Correspondence to Marcus Kaiser .

Editor information

Editors and Affiliations

  1. Atlanta, Georgia, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, Florida, USA

    Ranu Jung

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Kaiser, M. (2014). Neuropathologies and Networks. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_740-1

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_740-1

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-7320-6

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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