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Energy Balance and Gastrointestinal Cancer

  • Book
  • © 2012

Overview

Editors:
  1. Sanford D. Markowitz

    1. , Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Nathan A. Berger

    1. School of Medicine, Center for Science, Health & Society, Case Western Reserve University, Cleveland, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Explores relation between obesity and gastrointestinal cancer
  • Features up-to-date research
  • Examines the effects of physical activity on colon cancer prognosis
  • Includes supplementary material: sn.pub/extras

Part of the book series: Energy Balance and Cancer (EBAC, volume 4)

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About this book

The gastrointestinal track provides one of the distinct systems where multiple malignancies, including adenocarcinoma of the pancreas, esophagus and colon are each associated with obesity. This unique association is covered in this volume of Energy Balance and Cancer from the epidemiologic, biologic and potential etiologic viewpoint. The focus on possible dietary contribution as well as the role of exercise in prevention and therapy is presented in both animal model and patient based studies. Special focus is provided also on the role of genetic mutations and inflammatory pathways as drivers of these obesity related gastrointestinal malignancies. Overall, this volume on Energy Balance and Gastrointestinal Malignancies should be valuable to Epidemiologists, Gastroenterologists and Oncologists, as well as to students and researchers from multiple disciplines interested in understanding and disrupting the association between obesity and cancer.

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xii
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  2. Obesity and Gastrointestinal Cancers: Epidemiology

    • Nora L. Nock
    Pages 1-22

  3. Genetics of Colon Cancer Susceptibility

    • Graham Casey
    Pages 23-45

  4. Dietary Modulation of Colon Cancer: Effects on Intermediary Metabolism, Mucosal Cell Differentiation, and Inflammation

    • Lidija Klampfer, Barbara G. Heerdt, Anna Velcich, Erin Gaffney-Stomberg, Donghai Wang, Elaine Lin et al.
    Pages 47-64

  5. The ApcMin/+ Mouse Model to Study the Effects of Exercise on Gastrointestinal Malignancy

    • Nathan A. Berger
    Pages 65-75

  6. Obesity and the Pathogenesis of Barrett’s Esophagus

    • Rom Leidner, Amitabh Chak
    Pages 77-92

  7. Obesity and Pancreatic Cancer

    • Donghui Li
    Pages 93-109

  8. Obesity, Insulin Resistance Pathway Factors, and Colon Cancer

    • Li Li
    Pages 111-129

  9. Ras/Raf and Their Influence in Glycolysis in Colon Cancer

    • Fred Bunz, Nickolas Papadopoulos
    Pages 131-139

  10. Energy Balance and Other Modifiable Host Factors on Colorectal Cancer Prognosis

    • Jeffrey Meyerhardt
    Pages 141-156

  11. Cyclooxygenase-2 and Chronic Inflammation: Drivers of Colorectal Tumorigenesis

    • Monica M. Bertagnolli
    Pages 157-182

  12. Back Matter

    Pages 183-184
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Reviews

From the reviews:

“In this book, leading investigators present a crossdisciplinary (basic, translational, and clinical science) view of the current state of the science on the links between gastrointestinal malignancy and energy balance. … aimed at epidemiologists, gastroenterologists, and oncologists as well as students and researchers interested in understanding the connection between obesity and GI cancers … .” (Willem J. de Villiers, Doody’s Review Service, July, 2012)

Editors and Affiliations

  • , Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, USA

    Sanford D. Markowitz

  • School of Medicine, Center for Science, Health & Society, Case Western Reserve University, Cleveland, USA

    Nathan A. Berger

Bibliographic Information

  • Book Title: Energy Balance and Gastrointestinal Cancer

  • Editors: Sanford D. Markowitz, Nathan A. Berger

  • Series Title: Energy Balance and Cancer

  • DOI: https://doi.org/10.1007/978-1-4614-2367-6

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-4614-2366-9Published: 09 March 2012

  • Softcover ISBN: 978-1-4899-8970-3Published: 13 April 2014

  • eBook ISBN: 978-1-4614-2367-6Published: 09 March 2012

  • Series ISSN: 2199-2622

  • Series E-ISSN: 2199-2630

  • Edition Number: 1

  • Number of Pages: XII, 184

  • Topics: Cancer Research, Human Physiology

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