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Clinical, Immunological and Histopathological Evidence for Thymic Deficiency in Down’s Syndrome (Mongolism)

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Immune Reactivity of Lymphocytes

Abstract

Down’s syndrome (DS) is a chromosomal disorder leading to genetic malformations of various systems, the most marked giving rise to mental retardation and skeletal and heart abnormalities. The incidence of this disorder ranges from 1 per 1000 births in young mothers, to 1 per 50 births in mothers over 40 years of age. Certain clinical observations have recently lead investigators to study the immune system in DS.

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Author information

Authors and Affiliations

  1. The Pediatric Research Dept., Hebrew University — Hadassa Medical School, Jerusalem, Israel

    M. Schlesinger, S. Levin, Z. Handzel, T. Hahn & Y. Altman

  2. Pathology Dept., Hebrew University — Hadassa Medical School, Jerusalem, Israel

    B. Chernobilski

  3. Kaplan Hospital, Rehovot and Pathology Dept, Hebrew University — Hadassa Medical School, Jerusalem, Israel

    J. Bos

Authors
  1. M. Schlesinger
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  2. S. Levin
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  3. Z. Handzel
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  4. T. Hahn
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  5. Y. Altman
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  6. B. Chernobilski
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  7. J. Bos
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Editor information

Editors and Affiliations

  1. The Weizmann Institute of Science, Israel

    Michael Feldman  & Amiela Globerson  & 

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© 1976 Plenum Press, New York

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Schlesinger, M. et al. (1976). Clinical, Immunological and Histopathological Evidence for Thymic Deficiency in Down’s Syndrome (Mongolism). In: Feldman, M., Globerson, A. (eds) Immune Reactivity of Lymphocytes. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4355-4_103

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  • DOI: https://doi.org/10.1007/978-1-4613-4355-4_103

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4357-8

  • Online ISBN: 978-1-4613-4355-4

  • eBook Packages: Springer Book Archive

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