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Dynamic Interactions in Neural Networks: Models and Data pp 53–72Cite as

The Hippocampus and the Control of Information Storage in the Brain

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Part of the book series: Research Notes in Neural Computing ((NEURALCOMPUTING,volume 1))

Abstract

The present chapter assumes that the amount of information stored in the brain at a given moment is proportional to the mismatch between internally predicted events and the actual events ocurring in the external world. We have proposed ([29], [30]) that the hippocampus is involved in the computation of the “aggregate prediction” of ongoing events. This prediction is compared with information from the external world in order to determine the amount of information to be stored in the brain.

According to the “aggregate prediction” hypothesis (a) the effect of hippocampal lesions (HL) is an impairment in the integration of the aggregate prediction used to compute attentional variables (b) the effect of the induction of hippocampal long-term potentiation (LTP) is an increase in the value of the aggregate prediction by way of increasing the value of CS-CS associations and (c) that neural activity in hippocampus is proportional to the instantaneous value of the aggregate prediction. In addition, the present chapter introduces the hypothesis that medial septum activity is proportional to the sum of the values of different attentional variables.

The present chapter presents computer simulations for delay conditioning, conditioned inhibition, extinction, latent inhibition, and blocking for normal and HL cases. The “aggregate prediction” hypothesis proved capable of simulating most, but not all, experimental data regarding hippocampal manipulations in the rabbit nictitating membrane response preparation.

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Bibliography

  1. H. Anchel and D.B. Lindsley. Differentiation of two reticulo-hypothalamic systems regulating hippocampal activity. Electroencephalography and Clinical Neurophysiology, 32, 209–226, 1975.

    Article  Google Scholar 

  2. T.W. Berger. Long-term potentiation of hippocampal synaptic transmission affects rate of behavioral learning. Science, 224, 627–630, 1984.

    Article  Google Scholar 

  3. T.W. Berger and W.B. Orr. Hippocampectomy selectively disrupts discrimination reversal conditioning of the rabbit nictitating membrane response. Behavioral Brain Research, 8, 49–68, 1983.

    Article  Google Scholar 

  4. T.W. Berger and R.F. Thompson, Neuronal plasticity in the limbic system during classical conditioning of the rabbit nictitating membrane response. I. The hippocampus. Brain Research, 145, 323–346, 1978.

    Article  Google Scholar 

  5. G.A. Clark, D.A. McCormick, D.G. Lavond, and R.F. Thompson. Effects of lesions of cerebellar nuclei on conditioned behavioral and hippocampal neuronal responses. Brain Research, 291, 125–136, 1984.

    Article  Google Scholar 

  6. R. Douglas. Pavlovian conditioning and the brain. In R.A. Boeakes and M.S. Halliday (Eds.). Inhibition and Learning. London: Academic Press, 1972.

    Google Scholar 

  7. M.S. Gazzaniga. The biology of memory. In Neural Mechanism of Learning and Memory, M. Rosenzweig and E. Bennet (Eds.). Cambrige, MA: Mit Press, 1976.

    Google Scholar 

  8. M.S. Gazzaniga. Advances in cognitive neurosciences: The problem of information storage in the human brain. In Neurobiology of Learning and Memory, G. Lynch, J.L. McGaugh, and N.M. Weinberger (Eds.). New York: Guilford Press, 1984.

    Google Scholar 

  9. E. Grastyan, K. Lissak, I. Madaraz, and H. Donhoffer. Hippocampal electrical activity during the development of conditioned reflexes. Electroencephalography and Clinical Neurophysiology, 11, 409–430, 1959.

    Article  Google Scholar 

  10. P.C. Holland and R.A. Rescorla. Second-order conditioning with food unconditioned stimulus. Journal of Comparative and Physiological Psychology, 88, 459–467, 1975.

    Article  Google Scholar 

  11. H. Kaye and J.M. Pearce. The strength of the orienting response during Pavlovian conditioning. Journal of Experimental Psychology: Animal Behavior Processes, 10, 90–109, 1984.

    Article  Google Scholar 

  12. R.P. Kesner. An attribute analysis of memory: The role of hippocampus. Physiological Psychology, 8, 177–203, 1980.

    Google Scholar 

  13. C.M. Leyland. Higher-order autoshaping. Quarterly Journal of Experimental Psychology, 29, 607–619, 1977.

    Article  Google Scholar 

  14. B.L. McNaughton, CA. Barnes, G. Rao, J. Baldwin, and M. Rassmussen. Long-term enhancement of hippocampal synaptic transmission and the acquisition of spatial information. The Journal of Neuroscience, 6, 563–571, 1986.

    Google Scholar 

  15. D.J. Micco and M. Schwartz. Effects of hippocampal lesions upon the development of Pavlovian internal inhibition in rats. Journal of Comparative & Physiological Psychology, 76, 371–377, 1971.

    Article  Google Scholar 

  16. M. Mishkin and H.L. Petri. Memories and habits: Some implications for the analysis of learning and retention. In L.R. Squire and N. Butters (Eds.), Neuropsychology of Memory. New York: Guilford Press, 1984.

    Google Scholar 

  17. J.W. Moore. Brain processes and conditioning. In A. Dickinson and R.A. Boakes (Eds.), Mechanisms of Learning and Behavior. Hillsdale: Lawrence Erlbaum, 1979.

    Google Scholar 

  18. W.B. Orr and T.W. Berger. Hippocampectomy disrupts the topography of conditioned nictitating membrane responses during reversal learning. Journal of Comparative and Physiological Psychology, 99, 35–45, 1985.

    Google Scholar 

  19. J.M. Pearce and G. Hall. A model for Pavlovian learning: Variations in the effectiveness of conditioned but not of unconditioned stimuli. Psychological Review, 87, 532–552, 1980.

    Article  Google Scholar 

  20. R.L. Port and M.M. Patterson. Fimbrial lesions and sensory preconditioning. Behavioral Neuroscience, 98, 584–589, 1984.

    Article  Google Scholar 

  21. D.A. Powell and S. Buchanan. Autonomic-somatic relationships in the rabbit (Oryctolagus cuniculus): Effects of hippocampal leions. Physiological Psychology, 8, 455–462, 1980.

    Google Scholar 

  22. M.E. Rashotte, R.W. Griffin, and C.L. Sisk. Second-order conditioning of the pigeon’s keypeck. Animal Learning and Behavior, 5, 25–38, 1977.

    Article  Google Scholar 

  23. R.A. Rescorla. Simultaneous and succesive associations in sensory preconditioning. Journal of Experimental Psychology: Animal Behavior Processes, 6, 207–216, 1980.

    Article  Google Scholar 

  24. R.A. Rescorla and A.R. Wagner. A theory of Pavlovian conditioning: Variations in the effectiveness of reinforcement and non-reinforcement. In A. H. Black and W.F. Prokasy (Eds.), Classical Conditioning II: Theory and Research. New York: Appleton-Century-Crofts.

    Google Scholar 

  25. E.J. Rickert, J.F. Lorden, R. Dawson, E. Smyly, and M.F. Callahan. Stimulus processing and stimulus selection in rats with hippocampal lesions. Behavioral & Neural Biology, 27, 454–465, 1979.

    Article  Google Scholar 

  26. R.C. Rizley and R.A. Rescorla. Associations in second-order conditioning and sensory preconditioning, Journal of Comparative and Physiological Psychology, 81, 1–11, 1972.

    Article  Google Scholar 

  27. N. A. Schmajuk. A model for the effects of the hippocampal lesions on Pavlovian conditioning. Abstracts of the 14th Annual Meeting of the Society for Neuroscience, 10, 124, 1984.

    Google Scholar 

  28. N.A. Schmajuk. Real-time attentional models for classical conditioning and the hippocampus. Unpublished Doctoral Dissertation, University of Massachusetts, 1986.

    Google Scholar 

  29. N.A. Schmajuk and J.W. Moore. Real-time attentional models for classical conditioning and the hippocampus. Physiological Psychology, 13, 278–290, 1985.

    Google Scholar 

  30. N.A. Schmajuk and J.W. Moore. The hippocampus and the classically conditioned nictitating membrane response: A real-time attentional-associative model. In press, Psychobiology, 1988.

    Google Scholar 

  31. L.W. Schmaltz and J. Theios. Acquisition and extinction of a classically conditioned response in hippocampectomized rabbits (Oryctolagus cuniculus). Journal of Comparative and Physiological Psychology, 79, 328–333, 1972.

    Article  Google Scholar 

  32. E.N. Sokolov. Neuronal models and the orienting reflex. In M.A.B. Brazier (ed.), The Central Nervous System and Behavior, New York: Macy Foundation, 1960.

    Google Scholar 

  33. P.R. Solomon. Role of the hippocampus in blocking and conditioned inhibition of rabbit’s nictitating membrane response. Journal of Comparative and Physiological Psychology, 91, 407–417, 1977.

    Article  Google Scholar 

  34. P.R. Solomon and J.W. Moore. Latent inhibition and stimulus generalization of the classically conditioned nictitating membrane response in rabbits (Orytolagus cuniculus) following dorsal hippocampal ablation. Journal of Comparative and Physiological Psychology, 89, 1192–1203, 1975.

    Article  Google Scholar 

  35. R.F. Thompson and R.F. Kramer. Role of association cortex in sensory preconditioning. Journal of Comparative and Physiological Psychology, 60, 186–191, 1965.

    Article  Google Scholar 

  36. L. Squire. The neuropsychology of human memory. Annual Review of Neuroscience, 5, 241–273, 1982.

    Article  Google Scholar 

  37. E.C. Tolman. Cognitive maps in rats and men. Psychological Review, 55, 189–208, 1932.

    Article  Google Scholar 

  38. C.H. Vanderwolf, R. Kramis, L.A. Gillespie, and B.H. Bland. Hippocampal rhythmic slow activity and neocortical low-voltage fast activity: Relations to behavior. In R.L. Isaacson and K.H. Pribram (Eds.), The Hippocampus. New York: Plenum Press, 1975.

    Google Scholar 

  39. O.S. Vinogradova. Functional organization of the limbic system in the process of registration of information: Facts and hypotheses. In R.L. Isaacson and K.H. Pribram (Eds.), The hippocampus. New York: Plenum Press, 1975.

    Google Scholar 

  40. A.R. Wagner. Habituation and memory. In A. Dickinson and R.A. Boakes (Eds.), Mechanisms of learning and Motivation. Hillsdale, N.J.: Erlbaum, 1979.

    Google Scholar 

  41. W.A. Wickelgren. Chunking and consolidation: A theoretical synthesis of semantic networks, configuring in conditioning, S-R versus cognitive learnig, normal forgetting, the amnestic syndrome, and the hippocampal arousal system. Psychological Review, 86, 44–60, 1979.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Center for Adaptive Systems, Boston University, USA

    Nestor A. Schmajuk

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  1. Nestor A. Schmajuk
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Editor information

Editors and Affiliations

  1. Center for Neural Engineering, University of Southern California, Los Angeles, CA, 90089-0782, USA

    Michael A. Arbib

  2. Department of Mathematical Engineering and Instrumentation Physics, University of Tokyo, Tokyo, 113, Japan

    Shun-ichi Amari

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© 1989 Springer-Verlag New York Inc.

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Schmajuk, N.A. (1989). The Hippocampus and the Control of Information Storage in the Brain. In: Arbib, M.A., Amari, Si. (eds) Dynamic Interactions in Neural Networks: Models and Data. Research Notes in Neural Computing, vol 1. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4536-0_4

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  • DOI: https://doi.org/10.1007/978-1-4612-4536-0_4

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-96893-3

  • Online ISBN: 978-1-4612-4536-0

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