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Neuroendocrine Responses to Ethanol in the Prepubertal Female Rat

  • Chapter
Alcohol and Hormones

Part of the book series: Drug and Alcohol Abuse Reviews ((DAAR,volume 6))

Abstract

One of the most intriguing aspects of mammalian endocrinology is the complex synchronization of events that culminate in sexual maturity. The central nervous system plays a crucial role in bringing together these events by controlling both anterior pituitary function via the secretion of hypothalamic neuromodulators, and the ovary via pituitary hormone secretions and direct neural inputs. This being the case, a drug that is capable of affecting any one of these portions of the reproductive axis during development could cause serious manifestations to occur, which may affect the otherwise normal series of events leading to the onset of puberty. It is known that abuse of ethanol (ETOH) can cause reproductive endocrine problems in adult humans and laboratory animals, indicating that this is one such drug that has the potential to cause the same problems in adolescents. Many surveys indicate an alarming increase in adolescent and teenage ETOH abuse, which has sparked interest in learning more about the effects of ETOH on the sexual maturation process.

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  1. W. Les Dees
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  2. Christopher L. Nyberg
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  3. Jill K. Hiney
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  1. University of Arizona, Tucson, Arizona, USA

    Ronald R. Watson

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Dees, W.L., Nyberg, C.L., Hiney, J.K. (1995). Neuroendocrine Responses to Ethanol in the Prepubertal Female Rat. In: Watson, R.R. (eds) Alcohol and Hormones. Drug and Alcohol Abuse Reviews, vol 6. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0243-1_3

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  • DOI: https://doi.org/10.1007/978-1-4612-0243-1_3

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4612-6678-5

  • Online ISBN: 978-1-4612-0243-1

  • eBook Packages: Springer Book Archive

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