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Monitoring Cell Cytoskeleton Variations upon Piezoelectric Stimulation: Implications for the Immune System

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Cancer Immunotherapy

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2748))

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Abstract

Piezoelectric stimulation can have a significant impact on different cellular functions with possible applications in several fields, such as regenerative medicine, cancer therapy, and immunoregulation. For example, piezoelectric stimulation has been shown to modulate cytoskeleton variations: the implications of this effect range from the regulation of migration and invasion of cancer cells to the activation of pro- or anti-inflammatory phenotypes in immune cells. In this chapter, we will present different methodologies to evaluate cytoskeleton variations, focusing on modifications on f-/g-actin ratio and on the migration and invasion ability of tumor cells.

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Authors and Affiliations

  1. Istituto Italiano di Tecnologia, Smart Bio-Interfaces, Pontedera, Italy

    Özlem Şen, Carlotta Pucci & Gianni Ciofani

Authors
  1. Özlem Şen
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  2. Carlotta Pucci
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  3. Gianni Ciofani
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Corresponding author

Correspondence to Gianni Ciofani .

Editor information

Editors and Affiliations

  1. Synthetic and Systems Biology for Biomedicine, Isituto Italiano di Tecnologia-IIT, Napoli, Napoli, Italy

    Velia Siciliano

  2. Department of Chemical Engineering, Imperial College, London, UK

    Francesca Ceroni

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© 2024 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature

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Şen, Ö., Pucci, C., Ciofani, G. (2024). Monitoring Cell Cytoskeleton Variations upon Piezoelectric Stimulation: Implications for the Immune System. In: Siciliano, V., Ceroni, F. (eds) Cancer Immunotherapy. Methods in Molecular Biology, vol 2748. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3593-3_6

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  • DOI: https://doi.org/10.1007/978-1-0716-3593-3_6

  • Published:

  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-3592-6

  • Online ISBN: 978-1-0716-3593-3

  • eBook Packages: Springer Protocols

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