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Measuring the Full-Field Electroretinogram in Rodents

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Retinal Ganglion Cells

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2708))

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Abstract

Electroretinography allows for noninvasive functional assessment of the retina and is a mainstay for preclinical studies of retinal function in health and disease. The full-field electroretinogram is useful for a variety of applications as it returns a functional readout from each of the major cell classes within the retina: photoreceptors, bipolar cells, amacrine cells, and retinal ganglion cells. Rodent models are commonly employed in ocular degeneration studies due to the fast throughput of these mammalian species and the conservation of the electroretinogram from the preclinic to the clinic. Here we describe approaches for in vivo electroretinography in rodent models.

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Authors and Affiliations

  1. Department of Optometry and Vision Sciences, University of Melbourne, Parkville, VIC, Australia

    Pei Ying Lee, Da Zhao, Vickie H. Y. Wong, Anh Hoang, Katie K. N. Tran, Anna K. van Koeverden, Brianna C. Afiat, Christine T. O. Nguyen & Bang V. Bui

Authors
  1. Pei Ying Lee
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  2. Da Zhao
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  3. Vickie H. Y. Wong
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  4. Anh Hoang
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  5. Katie K. N. Tran
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  6. Anna K. van Koeverden
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  7. Brianna C. Afiat
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  8. Christine T. O. Nguyen
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  9. Bang V. Bui
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Corresponding author

Correspondence to Bang V. Bui .

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Editors and Affiliations

  1. School of Optometry and Vision Sciences, Cardiff University, Cardiff, UK

    Ben Mead

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© 2023 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature

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Lee, P.Y. et al. (2023). Measuring the Full-Field Electroretinogram in Rodents. In: Mead, B. (eds) Retinal Ganglion Cells. Methods in Molecular Biology, vol 2708. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3409-7_14

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  • DOI: https://doi.org/10.1007/978-1-0716-3409-7_14

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-3408-0

  • Online ISBN: 978-1-0716-3409-7

  • eBook Packages: Springer Protocols

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