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Biparental Crossing and QTL Mapping for Validation of Genome-Wide Association Studies

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Genome-Wide Association Studies

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2481))

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Abstract

Association mapping (AM), also known as genome-wide association studies (GWAS), is increasingly being employed in crop plants for the identification of QTL/genes and marker–trait associations (MTAs) in natural populations. Large numbers of such associations have been identified for variety of traits in different crop plants. However, not many of these associations have been used practically in the crop improvement program due to lack of validation. Although there are different ways through which the results of AM/GWAS could be validated, the best approach is to develop a biparental population for the trait of interest. An overview of the steps involved in the validation of results of AM using biparental mapping population in plants is provided in this chapter.

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Acknowledgments

During the course of writing this chapter, P. L. K. and R. S. received financial assistance from the Department of Biotechnology, Ministry of Science and Technology, Government of India, for a research project on wheat (Sanction No.102/IFD/SAN/3963/2019-20 dated 29.02.2020).

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Authors and Affiliations

  1. State Level Biotechnology Centre, Mahatma Phule Krishi Vidyapeeth, Rahuri, Ahmednagar, Maharashtra, India

    Pawan L. Kulwal

  2. School of Biotechnology, Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu, Jammu, Jammu and Kashmir, India

    Ravinder Singh

Authors
  1. Pawan L. Kulwal
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  2. Ravinder Singh
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Editor information

Editors and Affiliations

  1. Département de Phytologie, Université Laval, Quebec City, QC, Canada

    Davoud Torkamaneh

  2. Institut de biologie intégrative et des systems, Université Laval, Québec, QC, Canada

    François Belzile

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© 2022 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature

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Kulwal, P.L., Singh, R. (2022). Biparental Crossing and QTL Mapping for Validation of Genome-Wide Association Studies. In: Torkamaneh, D., Belzile, F. (eds) Genome-Wide Association Studies. Methods in Molecular Biology, vol 2481. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2237-7_16

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  • DOI: https://doi.org/10.1007/978-1-0716-2237-7_16

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-2236-0

  • Online ISBN: 978-1-0716-2237-7

  • eBook Packages: Springer Protocols

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