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Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems pp 313–339Cite as

Microbial Genetic Analysis Based on Field Effect Transistors

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Abstract

In this chapter, potentiometric detection methods for microbial DNA involved recognition events by use of genetic field effect devices will be described. Fundamental principles of field effect devices and the technical background with their ongoing applications in the field of bio-sensor technologies, termed bio-FET, will be first introduced. Then concept of genetic field effect transistor will be described with emphasis on their fabrication, characteristics, and recent applications to microbial Single Nucleotide Polymorphysms (SNPs) Analysis as well as DNA sequencing. By comparing to other conventional methods, technical significance and future perspective of the genetic field effect transistor will also be discussed in detail.

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Author information

Authors and Affiliations

  1. Biomaterials Center National Institute for Materials Science 1-1 Namiki, Tsukuba 305-0044, Japan

    Yuji Miyahara

  2. Department of Materials Engineering, Graduate School of Engineering The University of Tokyo, Tokyo, Japan

    Yuji Miyahara, Toshiya Sakata & Akira Matsumoto

Authors
  1. Yuji Miyahara
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  2. Toshiya Sakata
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  3. Akira Matsumoto
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Editors and Affiliations

  1. Biophage Pharma Inc, Montreal, Canada

    Mohammed Zourob

  2. Consultant to Biophage Pharma Inc, Montreal, Canada

    Souna Elwary

  3. Cranfield University, Bedfordshire, UK

    Anthony Turner

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Miyahara, Y., Sakata, T., Matsumoto, A. (2008). Microbial Genetic Analysis Based on Field Effect Transistors. In: Zourob, M., Elwary, S., Turner, A. (eds) Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems. Springer, New York, NY. https://doi.org/10.1007/978-0-387-75113-9_14

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  • DOI: https://doi.org/10.1007/978-0-387-75113-9_14

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