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Radiopharmaceuticals for Radioguided Surgery

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Radioguided Surgery

Abstract

The most common radioguided surgery procedure is sentinel lymph node localization with radiolabeled colloids. Cabanas described the sentinel node methodology in patients with penile cancer in his groundbreaking 1977 publication (1). In that study, sentinel lymph node localization was accomplished with lymphangiography, using iodinated contrast material. Lymphangiography requires cannulation of lymphatic channels for the direct injection of an oily iodinated contrast agent. Lymph nodes are visualized on the radiographs as the contrast material passes from the injection site through the node. In contrast to the radiographic technique, when using radiocolloids no skin incision is required to study lymphatic drainage from a specific site. As a result, the radionuclide technique has replaced the x-ray technique.

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Author information

Authors and Affiliations

  1. National Atomic Energy Commission, Ezeiza, Buenos Aires, Argentina

    Esteban Obenaus PhD

  2. Regional Center of Nuclear Medicine, University of Pisa Medical School, Pisa, Italy

    Paola A. Erba MD

  3. Division of Nuclear Medicine, European Institute of Oncology, Milan, Italy

    Marco Chinol PhD

  4. Division of Nuclear Medicine, University Hospital, Ghent, Belgium

    Christophe Van de Wiele MD & Rudy A. Dierckx MD

  5. Fodor Jozsef National Center of Public Health, Budapest, Hungary

    Gyozo A. Janoki PharmD, PhD

  6. Department of Nuclear Medicine and Molecular Imaging, University Hospital, Groningen, The Netherlands

    Rudy A. Dierckx MD

  7. Nuclear Medicine Unit, Department of Radiological Sciences, Second Medical School, University of Rome La Sapienza, Rome, Italy

    Francesco Scopinaro MD

  8. Department of Nuclear Medicine, University of Rome La Sapienza, Rome, Italy

    Alberto Signore MD

Authors
  1. Esteban Obenaus PhD
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  2. Paola A. Erba MD
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  3. Marco Chinol PhD
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  4. Christophe Van de Wiele MD
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  5. Gyozo A. Janoki PharmD, PhD
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  6. Rudy A. Dierckx MD
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  7. Francesco Scopinaro MD
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  8. Alberto Signore MD
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Editor information

Editors and Affiliations

  1. Regional Center of Nuclear Medicine, University of Pisa Medical School, Pisa, Italy

    Giuliano Mariani MD

  2. John Wayne Cancer Institute, Saint John’s Health Center, Santa Monica, California, USA

    Armando E. Giuliano MD (Chief of Science and Medicine) (Chief of Science and Medicine)

  3. Nuclear Medicine Service, Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA

    H. William Strauss MD

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© 2008 Springer Science+Business Media, LLC

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Obenaus, E. et al. (2008). Radiopharmaceuticals for Radioguided Surgery. In: Mariani, G., Giuliano, A.E., Strauss, H.W. (eds) Radioguided Surgery. Springer, New York, NY. https://doi.org/10.1007/978-0-387-38327-9_1

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  • DOI: https://doi.org/10.1007/978-0-387-38327-9_1

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-33684-8

  • Online ISBN: 978-0-387-38327-9

  • eBook Packages: MedicineMedicine (R0)

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