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A Review: Uses of Chitosan in Pharmaceutical Forms

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Reviews of Physiology, Biochemistry and Pharmacology

Abstract

Chitosan is a natural polysaccharide widespread in nature. It has many unique and attractive properties for the pharmaceutical field: it is biodegradable, safe, hypoallergenic, biocompatible with the body, free of toxicity, with proven anticholesterolemic, antibacterial, and antimycotic action. In this review we highlighted the physical, chemical, mechanical, mucoadhesive, etc. properties of chitosan to be taken into account when obtaining various pharmaceutical forms. The methods by which the pharmaceutical forms based on chitosan are obtained are very extensive, and in this study only the most common ones were presented.

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Abbreviations

DNA:

Deoxyribonucleic acid

HMWC:

High molecular weight chitosan

HPLC:

High-performance liquid chromatography

IR:

InfraRed

LD:

Lethal dose

LMWC:

Low molecular weight chitosan

MMWC:

Medium molecular weight chitosan

MRI:

Magnetic resonance imaging

O/W:

Oil/water

PVA:

Polyvinyl alcohol

PVP:

Polyvinylpyrrolidone

RNA:

Ribonucleic acid

UV:

Ultraviolet

W/O:

Water/oil

W/O/W:

Water/oil/water

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Correspondence to Narcis Duteanu .

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© 2021 The Author(s), under exclusive license to Springer Nature Switzerland AG

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Frenț, O.D. et al. (2021). A Review: Uses of Chitosan in Pharmaceutical Forms. In: Pedersen, S.H.F. (eds) Reviews of Physiology, Biochemistry and Pharmacology. Reviews of Physiology, Biochemistry and Pharmacology, vol 184. Springer, Cham. https://doi.org/10.1007/112_2021_69

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