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Immune Mechanisms in Inflammatory Bowel Disease

  • Book
  • © 2006

Overview

Editors:
  1. Richard S. Blumberg

    1. Gastroenterology Division and Laboratory of Mucosal Immunology, Brigham and Women’s Hospital, Harvard, USA

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  2. Markus F. Neurath

    1. 1st Department of Medicine, Johannes-Gutenberg-University, Mainz, Germany

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  • Includes chapters from major experts in the field internationally, making it a timely and highly considered piece of work

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 579)

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About this book

Immune Mechanisms in Inflammatory Bowel Disease is a highly, concise update of the most recent advances in the immunobiology, genetics and microbiology related to Inflammatory Bowel Disease. This book broadly treats the topics that lead to understanding of the pathogenesis of this disease in an organized, systematic approach.

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xv
    Download chapter PDF

  2. Structure and Function of the Gut Mucosal Immune System

    • Reinhard Pabst, Hermann J. Rothkötter
    Pages 1-14

  3. Functional Aspects of the Mucosal Immune System

    • Cathryn Nagler-Anderson
    Pages 15-23

  4. Recent Progress in Inflammatory Bowel Disease Genetics

    • Judy H. Cho
    Pages 24-34

  5. Microbial and Dietary Factors in the Pathogenesis of Chronic, Immune-Mediated Intestinal Inflammation

    • R. Balfour Sartor
    Pages 35-54

  6. Experimental Models of Mucosal Inflammation

    • Warren Strober, Ivan J. Fuss
    Pages 55-97

  7. Overview of Role of the Immune System in the Pathogenesis of Inflammatory Bowel Disease

    • Thomas T. MacDonald, Giovanni Monteleone
    Pages 98-107

  8. The Role of the Epithelial Barrier in Inflammatory Bowel Disease

    • Edward E. S. Nieuwenhuis, Richard S. Blumberg
    Pages 108-116

  9. Involvement of Dendritic Cells in the Pathogenesis of Inflammatory Bowel Disease

    • Francisco Leon, Lesley E. Smythies, Phillip D. Smith, Brian L. Kelsall
    Pages 117-132

  10. Alterations of T Lymphocytes in Inflammatory Bowel Diseases

    • Charles O. Elson, Yingzi Cong, Casey T. Weaver
    Pages 133-148

  11. The B-Cell System in Inflammatory Bowel Disease

    • Per Brandtzaeg, Hege S. Carlsen, Trond S. Halstensen
    Pages 149-167

  12. Alterations of Mesenchymal and Endothelial Cells in Inflammatory Bowel Diseases

    • Claudio Fiocchi, Kenji Ina, Silvio Danese, André Z. A. Leite, Jon D. Vogel
    Pages 168-176

  13. Role of Mast Cells and Eosinophils in Neuroimmune Interactions Regulating Mucosal Inflammation in Inflammatory Bowel Disease

    • Stephan C. Bischoff, Thomas Gebhardt
    Pages 177-208

  14. Multiparameter Analysis of Immunogenetic Mechanisms in Clinical Diagnosis and Management of Inflammatory Bowel Disease

    • Jonathan Braun, Stephan R. Targan
    Pages 209-218

  15. The Role of Probiotics and Antibiotics in Regulating Mucosal Inflammation

    • Rainer Duchmann
    Pages 219-226

  16. From Immunogenic Mechanisms to Novel Therapeutic Approaches in Inflammatory Bowel Disease

    • Martin H. Holtmann, Markus F. Neurath
    Pages 227-242

  17. Back Matter

    Pages 243-248
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Reviews

From the reviews:

"This multi-author book … provides a complete overview about intestinal immunology, thanks to the contribution of many of the leaders in this field. … The completeness of … articles allows the reader to consult the book rapidly in order to achieve direct information about the specific aspect he is interested in. This book can be recommended to both researchers interested in basic aspects of inflammatory bowel disease and clinical gastroenterologists who want to raise their awareness of the mechanisms underlying clinical manifestations … ." (A. Cassinotti, Digestive and Liver Disease, Vol. 39, 2007)

Editors and Affiliations

  • Gastroenterology Division and Laboratory of Mucosal Immunology, Brigham and Women’s Hospital, Harvard, USA

    Richard S. Blumberg

  • 1st Department of Medicine, Johannes-Gutenberg-University, Mainz, Germany

    Markus F. Neurath

Bibliographic Information

  • Book Title: Immune Mechanisms in Inflammatory Bowel Disease

  • Editors: Richard S. Blumberg, Markus F. Neurath

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/0-387-33778-4

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2006

  • Hardcover ISBN: 978-0-387-30831-9Published: 10 March 2006

  • Softcover ISBN: 978-1-4419-2157-4Published: 19 November 2010

  • eBook ISBN: 978-0-387-33778-4Published: 26 February 2007

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XVI, 248

  • Number of Illustrations: 32 b/w illustrations, 2 illustrations in colour

  • Topics: Medical Microbiology, Immunology, Microbiology

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