Abstract
In contrast to most other tissues, which exhibit considerable flexibility with respect to the nature of the substrates for their energy metabolism, the normal brain is restricted almost exclusively to glucose due to its distinguishing characteristics in vivo. Actual glucose utilization is 31 μmol/100 g tissue/min, in the normal, conscious human brain, indicating that glucose consumption is in excess for total oxygen consumption (Sokoloff, 1991). Although present in low concentration in brain (3.3 mmol/kg in rat), glycogen is a unique energy reserve for initiation of its metabolism. However, if glycogen concentration in the brain were the sole supply, normal energetic requirements would be maintained for less than 5 min (Sokoloff, 1991).
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MONTERO, S., CADENAS, J., LEMUS, M., ÁLVAREZ-BUYLLA., E.R., ÁLVAREZ-BUYLLA., R. (2006). Nitric Oxide in Brain Glucose Retention after Carotid Body Receptors Stimulation with Cyanide in Rats. In: Hayashida, Y., Gonzalez, C., Kondo, H. (eds) THE ARTERIAL CHEMORECEPTORS. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, vol 580. Springer, Boston, MA. https://doi.org/10.1007/0-387-31311-7_45
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DOI: https://doi.org/10.1007/0-387-31311-7_45
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