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Animal Models of Leptomeningeal Cancer

  • Chapter
Leptomeningeal Metastases

Part of the book series: Cancer Treatment and Research ((CTAR,volume 125))

Abstract

Animal models are a critical tool for our understanding of pathogenic mechanisms and the development of therapeutic strategies. Since the 1970's, numerous syngeneic and allogeneic rodent models of leptomeningeal cancer have been developed; in this chapter, we present representative models and discuss their clinical and translational implications.

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Authors and Affiliations

  1. University of Illinois at Chicago, Chicago, IL, 60612

    Ali Raja M.D. & Herbert H. Engelhard M.D., Ph.D.

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  1. Ali Raja M.D.
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  2. Herbert H. Engelhard M.D., Ph.D.
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Editors and Affiliations

  1. Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10021

    Lauren E. Abrey M.D.

  2. Department of Neurology, University of Southern California, Norris Comprehensive Cancer Center and Hospital, Los Angeles, CA, 90033

    Marc C. Chamberlain M.D.

  3. Departments of Neurosurgery, Bioengineering & Molecular Genetics, University of Illinois at Chicago, Chicago, IL, 60612

    Herbert H. Engelhard M.D., PhD.

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Raja, A., Engelhard, H.H. (2005). Animal Models of Leptomeningeal Cancer. In: Abrey, L.E., Chamberlain, M.C., Engelhard, H.H. (eds) Leptomeningeal Metastases. Cancer Treatment and Research, vol 125. Springer, Boston, MA. https://doi.org/10.1007/0-387-24199-X_10

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