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Immunosuppressive activity of mesenchymal stem cells is not decreased in children with aplastic anemia

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References

  1. Young NS, Maciejewski J. The pathophysiology of acquired aplastic anemia. N Engl J Med. 1997;336(19):1365–72. doi:10.1056/NEJM199705083361906.

    Article  CAS  PubMed  Google Scholar 

  2. Ascensao J, Pahwa R, Kagan W, Hansen J, Moore M, Good R. Aplastic anaemia: evidence for an immunological mechanism. Lancet. 1976;1(7961):669–71. doi:10.1016/S0140-6736(76)92780-X.

    Article  CAS  PubMed  Google Scholar 

  3. Di Nicola M, Carlo-Stella C, Magni M, Milanesi M, Longoni PD, Matteucci P, et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood. 2002;99(10):3838–43. doi:10.1182/blood.V99.10.3838.

    Article  CAS  PubMed  Google Scholar 

  4. Bartholomew A, Sturgeon C, Siatskas M, Ferrer K, McIntosh K, Patil S, et al. Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp Hematol. 2002;30(1):42–8. doi:10.1016/S0301-472X(01)00769-X.

    Article  PubMed  Google Scholar 

  5. Bacigalupo A, Valle M, Podesta M, Pitto A, Zocchi E, De Flora A, et al. T-cell suppression mediated by mesenchymal stem cells is deficient in patients with severe aplastic anemia. Exp Hematol. 2005;33(7):819–27. doi:10.1016/j.exphem.2005.05.006.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan

    Yinyan Xu, Yoshiyuki Takahashi, Ayami Yoshimi, Makito Tanaka, Hiroshi Yagasaki & Seiji Kojima

Authors
  1. Yinyan Xu
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  2. Yoshiyuki Takahashi
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  3. Ayami Yoshimi
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  4. Makito Tanaka
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  5. Hiroshi Yagasaki
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  6. Seiji Kojima
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Corresponding author

Correspondence to Seiji Kojima.

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Xu, Y., Takahashi, Y., Yoshimi, A. et al. Immunosuppressive activity of mesenchymal stem cells is not decreased in children with aplastic anemia. Int J Hematol 89, 126–127 (2009). https://doi.org/10.1007/s12185-008-0237-6

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  • DOI: https://doi.org/10.1007/s12185-008-0237-6

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