Abstract
Compression therapy is still not widely used for patients with deep vein thrombosis (DVT). This report provides information on Italian doctors’ use of elastic stockings (ES) after acute DVT and identifies some predictors of prescription. Material and methods The MASTER multicenter registry collected information about clinical characteristics and management of patients with venous thromboembolism (VTE). In patients with objectively confirmed acute VTE, information about clinical presentation, diagnostic methods, temporary and permanent risk factors, pre-event prophylaxis and treatment, including ES prescription, were captured by an electronic data network at the time of the index event. Results Of 2119 patients enrolled, 1913 had DVT, 1772 in the legs; 1277 were prescribed ES at hospital discharge. The following conditions were associated with more frequent prescription: edema, in-hospital management, known thrombophilia; younger age. In multivariate analysis these factors all remained significantly associated with more frequent use of ES. Conclusions Italian clinicians’ attitudes to prescribing ES still appear suboptimal. Special attention is needed for patients treated at home, where organizational problems can interfere with the use of ES.
Similar content being viewed by others
References
Kolbach DN, Sandbrink MW, Hamulyak K, Neumann HA, Prins MH (2004) Nonpharmaceutical measures for prevention of post-thrombotic syndrome. Cochrane Database Syst Rev (1):CD004174
Kakkos SK, Daskalopoulou SS, Daskalopoulos ME, Nicolaides AN, Geroulakos G (2006) Review on the value of graduated elastic compression stockings after deep vein thrombosis. Thromb Haemost 96:441–445
Belcaro G, Laurora G, Cesarone MR, De Sanctis MT (1993) Prophylaxis of recurrent deep venous thrombosis. A randomized, prospective study using indobufen and graduated elastic compression stockings. Angiology 44:695–699. doi:10.1177/000331979304400904
Kearon C, Kahn SR, Agnelli G, Goldhaber S, Raskob GE, Comerota AJ, American College of Chest Physicians (2008) Antithrombotic therapy for venous thromboembolic disease: American College of chest physicians evidence-based clinical practice guidelines (8th edn). Chest 133(6)(Suppl):454S–545S. doi:10.1378/chest.08-0658
Caprini JA, Tapson VF, Hyers TM, Waldo AL, Wittkowsky AK, Friedman R, Colgan KJ, Shillington AC, NABOR Steering Committee (2005) Treatment of venous thromboembolism: adherence to guidelines and impact of physician knowledge, attitudes, and beliefs. J Vasc Surg 42:726–733. doi:10.1016/j.jvs.2005.05.053
Wittkowsky AK, Nutescu EA, Devine EB (2007) Compression stockings to prevent post-thrombotic syndrome: a role for anticoagulation clinics? J Thromb Thrombolysis [Epub ahead of print]
Kahn SR, Elman E, Rodger MA, Wells PS (2003) Use of elastic compression stockings after deep venous thrombosis: a comparison of practices and perceptions of thrombosis physicians and patients. J Thromb Haemost 1:500–506. doi:10.1046/j.1538-7836.2003.00098.x
Agnelli G, Verso M, Ageno W, Imberti D, Moia M, Palareti G, Rossi R, Pistelli R (2008) MASTER investigators. The MASTER registry on venous thromboembolism: description of the study cohort. Thromb Res 121:605–610. doi:10.1016/j.thromres.2007.06.009
Arcelus JI, Monreal M, Caprini JA, Guisado JG, Soto MJ, Núñez MJ, Alvárez JC (2008) RIETE investigators. Clinical presentation and time-course of postoperative venous thromboembolism: results from the RIETE Registry. Thromb Haemost 99:546–551
Hyers TM, Agnelli G, Hull RD, Morris TA, Samama M, Tapson V, Weg JG (2001) Antithrombotic therapy for venous thromboembolic disease. Chest 119(1)(Suppl):176S–193S. doi:10.1378/chest.119.1_suppl.176S
Büller HR, Agnelli G, Hull RD, Hyers TM, Prins MH, Raskob GE (2004) Antithrombotic therapy for venous thromboembolic disease: the seventh ACCP conference on antithrombotic and thrombolytic therapy. Chest 126(3)(Suppl):401S–428S. doi:10.1378/chest.126.3_suppl.401S
Prandoni P, Lensing AW, Prins MH, Frulla M, Marchiori A, Bernardi E, Tormene D, Mosena L, Pagnan A, Girolami A (2004) Below-knee elastic compression stockings to prevent the post-thrombotic syndrome: a randomized, controlled trial. Ann Intern Med 141:249–256
Brandjes DP, Büller HR, Heijboer H, Huisman MV, de Rijk M, Jagt H, ten Cate JW (1997) Randomised trial of effect of compression stockings in patients with symptomatic proximal-vein thrombosis. Lancet 349:759–762. doi:10.1016/S0140-6736(96)12215-7
van Dongen CJ, Prandoni P, Frulla M, Marchiori A, Prins MH, Hutten BA (2005) Relation between quality of anticoagulant treatment and the development of the post-thrombotic syndrome. J Thromb Haemost 3:939–942. doi:10.1111/j.1538-7836.2005.01333.x
Ziegler S, Schillinger M, Maca TH, Minar E (2001) Post-thrombotic syndrome after primary event of deep venous thrombosis 10 to 20 years ago. Thromb Res 101:23–33. doi:10.1016/S0049-3848(00)00370-4
Ageno W, Grimwood R, Limbiati S, Dentali F, Steidl L, Wells P (2005) Home treatment of deep vein thrombosis in patients with cancer. Haematologica 90:220–224
Author information
Authors and Affiliations
Corresponding author
Additional information
List of MASTER Investigators are given in Appendix section.
Appendix: Participating investigators and study sites
Appendix: Participating investigators and study sites
Study Coordinator: G. Agnelli, Azienda Ospedaliera di Perugia, Università di Perugia, Perugia. Investigators: R. Rossi and M. Verso Azienda Ospedaliera di Perugia, Università di Perugia, Perugia.; W. Ageno and J. Vitale, Ospedale di Circolo Macchi, Varese; M. Bellisi, Policlinico “Paolo Giaccone”, Palermo; M. Bianchi, Ospedale Valduce, Como; V. Brancaccio, Ospedale Cardarelli, Napoli; A. Ciampa, Azienda Ospedaliera San Giovanni Moscati, Avellino; A. Dragani, Ospedale Civile di Pescara, Pescara; S. Grifoni, Azienda Ospedaliera Careggi, Firenze; D. Imberti, Ospedale Civile di Piacenza, Piacenza; M. Impagliatelli, IRCCS Casa Sollievo della Sofferenza, S. Giovanni Rotondo (FG); G. Iovane, ASL Bianchi Melacrino- Morelli, Reggio Calabria; R. Margheriti, Ospedale G.B. Grassi, Ostia Lido (RM); M. Moia, Ospedale Maggiore di Milano, Milano; A. Musumeci, Ospedale Vittorio Emanuele II, Catania; G. Palareti, Policlinico S. Orsola Malpigli, Bologna; M. Pini, Ospedale Civile di Fidenza, Fidenza (PR); P.A. Pittaluga, Ospedale Galliera, Genova; V. Prisco, Ospedale ASL SA/2, Mercato San Severino (SA); S. Rupoli, Ospedale Regionale Torrette, Torrette di Ancona (AN); G. Scannapieco, Ospedale Civile Ca’ Foncello, Treviso; S. Signorelli, Ospedale Garibaldi, Catania; M. Silingardi, Azienda Ospedaliera S. Maria Nuova, Reggio Emilia; S. Siragusa, Policlinico “Paolo Giaccone”, Palermo; V. Virgilio, Ospedale Garibaldi, Catania.
Rights and permissions
About this article
Cite this article
Arpaia, G., Carpenedo, M., Pistelli, R. et al. Attitudes to prescribing compression stockings for patients with acute dvt: the MASTER registry. J Thromb Thrombolysis 28, 389–393 (2009). https://doi.org/10.1007/s11239-009-0316-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11239-009-0316-4