Abstract
Congenital biliary dilatation (CBD) of different types was recently noted in dizygotic twins. Our cases suggest the possibility of hereditary involvement in CBD. On the other hand, CBD discordance in six sets of monozygotic twins has been reported, which would suggest that the occurrence of CBD is not compatible with single gene control, although environmental factors are plausible. To evaluate the genetic factors that may be implicated in CBD, it would be necessary to accumulate more familial cases and examine further studies on inheritance.
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References
Schweizer P (1995) Pathogenesis of choledochal cyst. A hereditary disease? Pediatr Surg Int 10:475–477
Iwama T, Iwata S, Murakami S, et al. (1985) Congenital bile duct dilatation, possibly an hereditary condition. Jpn J Surg 15:501–505
Narita H, Wakasugi T, Kato K, et al. (1996) Congenital biliary dilatation occurred in a mother and her child. Nihon Rinshogeka Gakkai Zasshi 57:2254–2258 (in Japanese, English abstract)
Iwama T (1994) Congenital bile dilatation. Jpn J Pediatr Surg 26:362–365 (in Japanese, English abstract)
Iwafuchi M, Ohsawa Y, Naito S, et al. (1990) Familial occurrence of congenital bile duct dilatation. J Pediatr Surg 25:353–355
Date M, Sugimoto S, Kawasaki S, et al. (1987) Familial congenital cystic dilatation of common bile duct. Jpn J Gastroent Surg 20:2631–2634 (in Japanese)
Chiba T, Obashi E, Uchida T, et al. (1981) Congenital bile duct dilatation in siblings. Z.Kinderchir 32:188–190
Lane GJ, Yamataka A, Kobayashi H, et al. (1999) Different types of congenital biliary dilatation in dizygotic twins. Pediatr Surg Int 15:403–404
Uchida M, Tsukahara M, Fuji T, et al. (1992) Discordance for anomalous pancreaticobiliary ductal junction and congenital biliary dilatation in a set of monozygotic twins. J Pediatr Surg 27:1563–1564
Urushibara N, Todani T, Watanabe Y, et al. (1988) Choledochal cyst in an identical twin. Jpn J Pediatr Surg 20:653–657 (in Japanese, English abstract)
Narita H, Tsuruga N, Hashimoto T, et al. (1990) Congenital choledocal dilatasion in one of monozygotic twins. J Jpn Soc Pediatr Surg 26:671–677 (in Japanese, English abstract)
Yamataka A, Kuwatsuru R, Shima H, et al. (1997) Initial experience with non-breath-hold magnetic resonance cholangiopancreatography: a new noninvasive technique for the diagnosis of choledochal cyst in children. J Pediatr Surg 32:1560–1562
Hamada Y, Tanano A, Watanabe K, et al. (2004) Preoperative biliary imaging for children with pancreaticobiliary maljunction: Magnetic resonance cholangiopancreatography or intravenous cholangiography—spiral computed tomography. Jpn J Pediatr Surg 36:440–444
Hamada Y, Tanano A, Takada K, et al. (2004) Magnetic resonance cholangiopancreatography on postoperative work-up in children with choledochal cysts. Pediatr Surg Int 20:43–46
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Tokuhara, K., Hamada, Y., Yui, R. et al. Congenital biliary dilatation in dizygotic twins. Ped Surgery Int 21, 17–19 (2005). https://doi.org/10.1007/s00383-004-1255-y
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DOI: https://doi.org/10.1007/s00383-004-1255-y