Skip to main content

Advertisement

Log in

Encapsulated fat necrosis mimicking subcutaneous liposarcoma: radiologic findings on MR, PET-CT, and US imaging

  • Case Report
  • Published:
Skeletal Radiology Aims and scope Submit manuscript

Abstract

We present a case of a subcutaneous encapsulated fat necrosis of the upper extremity that mimicked subcutaneous liposarcoma because of heterogeneous signal intensity, its relatively large size, and pronounced enhancement on magnetic resonance imaging (MRI). For this case, we present the radiologic findings including MRI, positron emission tomography-computed tomography (PET-CT), ultrasonography, and radiography. We emphasize the imaging features of this lesion, which has a fibrous capsule and briefly discuss its nomenclature and pathophysiology.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

References

  1. Hurt MA, Santa Cruz DJ. Nodular-cystic fat necrosis. A reevaluation of the so-called mobile encapsulated lipoma. J Am Acad Dermatol. 1989;21(3 Pt 1):493–8.

    Article  PubMed  CAS  Google Scholar 

  2. Schmidt-Hermes HJ, Loskant G. Calcified fat necrosis of the female breast. Med Welt. 1975;26(24):1179–80.

    PubMed  CAS  Google Scholar 

  3. Canteli B, Saez F, de los Rios A, Alvarez C. Fat necrosis. Skelet Radiol. 1996;25(3):305–7.

    Article  CAS  Google Scholar 

  4. Lopez JA, Saez F, Alejandro Larena J, Capelastegui A, Martin JI, Canteli B. MRI diagnosis and follow-up of subcutaneous fat necrosis. J Magn Reson Imaging: JMRI. 1997;7(5):929–32.

    Article  PubMed  CAS  Google Scholar 

  5. Walsh M, Jacobson JA, Kim SM, Lucas DR, Morag Y, Fessell DP. Sonography of fat necrosis involving the extremity and torso with magnetic resonance imaging and histologic correlation. J Ultrasound Med: Off J Am Inst Ultrasound Med. 2008;27(12):1751–7.

    Google Scholar 

  6. Przyjemski CJ, Schuster SR. Nodular-cystic fat necrosis. J Pediatr. 1977;91(4):605–7.

    Article  PubMed  CAS  Google Scholar 

  7. Kikuchi I, Okazaki M, Narahara S. The so-called mobile encapsulated lipoma. J Dermatol. 1984;11(4):410–2.

    PubMed  CAS  Google Scholar 

  8. Sahl Jr WJ. Mobile encapsulated lipomas. Formerly called encapsulated angiolipomas. Arch Dermatol. 1978;114(11):1684–6.

    Article  PubMed  Google Scholar 

  9. Kikuchi I. Encapsulated necrosis on the legs showing a changing number of nodules. A special type of encapsulated adiponecrosis? J Dermatol. 1984;11(4):413–6.

    PubMed  CAS  Google Scholar 

  10. Felipo F, Vaquero M, del Agua C. Pseudotumoral encapsulated fat necrosis with diffuse pseudomembranous degeneration. J Cutan Pathol. 2004;31(8):565–7.

    Article  PubMed  CAS  Google Scholar 

  11. Kiryu H, Rikihisa W, Furue M. Encapsulated fat necrosis—a clinicopathological study of 8 cases and a literature review. J Cutan Pathol. 2000;27(1):19–23.

    Article  PubMed  CAS  Google Scholar 

  12. Ohtake N, Gushi A, Matsushita S, Kanzaki T. Encapsulated fat necrosis in a patient with Ehlers-Danlos syndrome. J Cutan Pathol. 1997;24(3):189–92.

    Article  PubMed  CAS  Google Scholar 

  13. Takao H, Yamahira K, Watanabe T. Encapsulated fat necrosis mimicking abdominal liposarcoma: computed tomography findings. J Comput Assist Tomogr. 2004;28(2):193–4.

    Article  PubMed  Google Scholar 

  14. Yi-Hsin H, Ya-Wen H, Yi-Chin S. Multiple floating fat balls on the right lower leg. Nodular cystic fat necrosis. Indian J Dermatol Venereol Leprol. 2011;77(6):731–2.

    PubMed  Google Scholar 

  15. Pujol RM, Wang CY, Gibson LE, Su WP. Lipomembranous changes in nodular-cystic fat necrosis. J Cutan Pathol. 1995;22(6):551–5.

    Article  PubMed  CAS  Google Scholar 

  16. Oh CW, Kim KH. A case of nodular cystic fat necrosis: the end stage lesion showing calcification and lipomembranous changes. J Dermatol. 1998;25(9):616–21.

    PubMed  CAS  Google Scholar 

  17. Hanami Y, Hiraiwa T, Yamamoto T. Nodular cystic fat necrosis with calcification and metaplastic ossification. Am J Dermatopathol. 2012;34(7):782–4.

    Article  PubMed  Google Scholar 

  18. Brooke BS, Choti MA. Image of the month. Encapsulated fat necrosis. Arch Surg. 2011;146(12):1447–8.

    Article  PubMed  Google Scholar 

  19. Andac N, Baltacioglu F, Cimsit NC, Tuney D, Aktan O. Fat necrosis mimicking liposarcoma in a patient with pelvic lipomatosis. CT findings. Clin Imaging. 2003;27(2):109–11.

    Article  PubMed  Google Scholar 

  20. Adejolu M, Huo L, Rohren E, Santiago L, Yang WT. False-positive lesions mimicking breast cancer on FDG PET and PET/CT. AJR Am J Roentgenol. 2012;198(3):W304–14.

    Article  PubMed  Google Scholar 

  21. Belakhlef A, Jani C, Church C, Fraser R, Lakhanpal S. Fat necrosis mimicking B-cell lymphoma: a PET/CT and FDG study. Clin Nucl Med. 2008;33(4):271–2.

    Article  PubMed  Google Scholar 

  22. Barile A, Zugaro L, Catalucci A, Caulo M, Di Cesare E, Splendiani A, et al. Soft tissue liposarcoma: histological subtypes, MRI and CT findings. Radiol Med. 2002;104(3):140–9.

    PubMed  CAS  Google Scholar 

  23. El Ouni F, Jemni H, Trabelsi A, Ben Maitig M, Arifa N, Ben Rhouma K, et al. Liposarcoma of the extremities: MR imaging features and their correlation with pathologic data. Orthop Traumatol Surg Res: OTSR. 2010;96(8):876–83.

    Article  PubMed  Google Scholar 

  24. Murphey MD, Arcara LK, Fanburg-Smith J. From the archives of the AFIP: imaging of musculoskeletal liposarcoma with radiologic-pathologic correlation. Radiographics: Rev Publ Radiol Soc N Am Inc. 2005;25(5):1371–95.

    Google Scholar 

  25. Murphey MD, Carroll JF, Flemming DJ, Pope TL, Gannon FH, Kransdorf MJ. From the archives of the AFIP: benign musculoskeletal lipomatous lesions. Radiographics: Rev Publ Radiol Soc N Am Inc. 2004;24(5):1433–66.

    Google Scholar 

  26. Drevelegas A, Pilavaki M, Chourmouzi D. Lipomatous tumors of soft tissue: MR appearance with histological correlation. Eur J Radiol. 2004;50(3):257–67.

    Article  PubMed  CAS  Google Scholar 

  27. Toirkens J, De Schepper AM, Vanhoenacker F, Van Dyck P, Gielen J, Creytens D, et al. A comparison between histopathology and findings on magnetic resonance imaging of subcutaneous lipomatous soft-tissue tumors. Insights Imaging. 2011;2(5):599–607.

    Article  PubMed  Google Scholar 

  28. Bancroft LW, Kransdorf MJ, Peterson JJ, Sundaram M, Murphey MD, O'Connor MI. Imaging characteristics of spindle cell lipoma. AJR Am J Roentgenol. 2003;181(5):1251–4.

    Article  PubMed  Google Scholar 

  29. Bolen JW, Thorning D. Spindle-cell lipoma. A clinical, light- and electron-microscopical study. Am J Surg Pathol. 1981;5(5):435–41.

    Article  PubMed  CAS  Google Scholar 

Download references

Conflict of interest

We had no financial conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hye Won Chung.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lee, S.A., Chung, H.W., Cho, K.J. et al. Encapsulated fat necrosis mimicking subcutaneous liposarcoma: radiologic findings on MR, PET-CT, and US imaging. Skeletal Radiol 42, 1465–1470 (2013). https://doi.org/10.1007/s00256-013-1647-y

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00256-013-1647-y

Keywords

Navigation