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Risk factors for hip fracture in older adults: a case–control study in Taiwan

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Abstract

Summary

We conducted a matched case–control study of hip fracture in older adults. Our findings suggest that hip fracture risk was determined by multiple factors. Older women characterized by low consumption of milk, peak flow rate, grip strength, and bone mineral density (BMD) had increased risk of hip fracture. Older men with impaired cognitive function and low BMD were also at higher risk of hip fracture.

Introduction

Multiple factors contribute to low-trauma hip fracture in older adults. The aim of this study was to determine important characteristics of hip fracture in older population.

Methods

A total of 228 patients with first low-trauma hip fracture were matched with 497 controls. All 77 potential risk factors of hip fracture organized into 13 groups were analyzed using conditional logistic regression.

Results

Low milk intake, peak flow rate, hand grip strength, and bone mineral density in women and low mini-mental state examination score and bone mineral density in men were further identified to be independently associated with elevated hip fracture risk.

Conclusions

The factors found in our study may help understand the etiology of hip fracture and be further adopted to evaluate the risk of hip fracture in community and clinical setting.

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Acknowledgments

The study was supported by the National Health Research Institutes in Taiwan (Project GE-093-PP-05 & GE-094-PP-06). We thank the study participants, including patients and community-dwellers, who were fully informed and agreed to participate in the study, for their generous support and collaboration. We also thank Shu-Hui Lin and Hsiu-Ling Liao for their help in recruiting and training the interviewers. Our appreciation further goes to the ten interviewers for their efforts to conduct the interviewing work, and the following persons in the National Taiwan University Hospital for their help in collecting the data: Mei-Huei Lai, Yu-Sin Chen, Rong-Huei Lin, Ling-Juan Shen, Hsiu-Yun Lai, Ling-Yu Hong, and Yung-Chao Lei.

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Correspondence to T.-Y. Tai.

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Lan, TY., Hou, SM., Chen, CY. et al. Risk factors for hip fracture in older adults: a case–control study in Taiwan. Osteoporos Int 21, 773–784 (2010). https://doi.org/10.1007/s00198-009-1013-z

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  • DOI: https://doi.org/10.1007/s00198-009-1013-z

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