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Seltene Ursache eines akuten Leberversagens

Rare cause of acute liver failure

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Zusammenfassung

Eine sehr seltene Ursache des akuten Leberversagens ist der adulte Morbus Still, eine systemische rheumatische Erkrankung. Wir berichten von einer 24-jährigen Frau mit unklarem akutem Leberversagen. Aufgrund des fulminanten Verlaufs wurde eine Lebertransplantation erforderlich. Die Diagnose des Morbus Still konnte unter Berücksichtigung der Yamaguchi-Kriterien mit Arthralgien, Fieber, Halsschmerzen, Hauterscheinungen und Hepatosplenomegalie gestellt werden. Die frühzeitige Diagnose und Therapie eines Morbus Still kann die Entwicklung eines akuten Leberversagens mit hoher Letalität verhindern.

Abstract

A rare cause of acute liver failure is adult onset Still’s disease (AOSD), a systemic inflammatory disorder. We present the case of a 24-year-old woman who presented with acute liver failure necessitating high urgency liver transplantation. The diagnosis of AOSD was established in accordance with the Yamaguchi classification criteria, including arthralgia, fever, sore throat, rash and hepatosplenomegaly. The early detection and therapy of AOSD can possibly avoid the development of liver failure with a poor prognosis.

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Authors and Affiliations

  1. Klinik für Allgemein- und Viszeralchirurgie, Klinikum der Johann Wolfgang Goethe Universität Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland

    J. Liese, T. Schreckenbach, F. Ulrich, W.O. Bechstein & C. Moench

  2. Medizinische Klinik II, Rheumatologie, Klinikum der Johann Wolfgang Goethe Universität Frankfurt, Frankfurt am Main, Deutschland

    M. Wahle

  3. Medizinische Klinik I, Gastroenterologie und Hepatologie, Klinikum der Johann Wolfgang Goethe Universität Frankfurt, Frankfurt am Main, Deutschland

    M.W. Welker

Authors
  1. J. Liese
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  2. T. Schreckenbach
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  3. M. Wahle
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  4. M.W. Welker
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  5. F. Ulrich
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  6. W.O. Bechstein
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  7. C. Moench
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Correspondence to J. Liese.

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Liese, J., Schreckenbach, T., Wahle, M. et al. Seltene Ursache eines akuten Leberversagens. Chirurg 83, 732–735 (2012). https://doi.org/10.1007/s00104-012-2314-x

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  • DOI: https://doi.org/10.1007/s00104-012-2314-x

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