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Mechanism of Michael addition of ethyl acetoacetate to chalcone catalyzed by activated Ba(OH)2

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Abstract

Preliminary studies of the mechanism of Michael addition of ethyl acetoacetate to chalcone are presented. Different products may be obtained with good yields (≧80%) and selectivities (≃100%), under different reaction conditions. A mechanism based on the geometric characteristics of the active site of activated barium hydroxide (C-200) is proposed.

Abstract

Проведены предварительные исследования механизма реакции присоединения Михаэля этилацетоацетата к халкону. При различных условиях различные продукты были получены с хорошим выходом (≧80%) и селективностью (⋟100%). Предложенный механизм основан на геометрических характеристиках активных центров активированной гидроокиси бария (C-200).

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Authors and Affiliations

  1. Departamento de Quimica Orgánica, Universidades de Palma de Mallorca y Córdoba, Spain

    J. V. Sinisterra

Authors
  1. A. Garcia-Raso
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  2. J. A. Garcia-Raso
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  3. R. Mestres
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  4. J. V. Sinisterra
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Garcia-Raso, A., Garcia-Raso, J.A., Mestres, R. et al. Mechanism of Michael addition of ethyl acetoacetate to chalcone catalyzed by activated Ba(OH)2 . React Kinet Catal Lett 28, 365–371 (1985). https://doi.org/10.1007/BF02062966

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  • DOI: https://doi.org/10.1007/BF02062966

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