Skip to main content
SpringerLink
Log in

Primary mediastinal large B-cell lymphoma mimicking liposarcoma

  • CASE
  • Published:
Medical Oncology Aims and scope Submit manuscript

Abstract

A 78-year-old man consulted for acute exacerbation of chronic obstructive pulmonary disease (COPD) and an incidental finding of an anterior mediastinal tumor on chest radiograph was noted on admission. Chest computed tomography (CT) revealed a fat-containing mediastinal mass with solid component. Mediastinal liposarcoma was the initial diagnosis based on image characteristics but histopathologic examination of the excised tumor revealed lymphoma infiltration of the mediastinal adipose tissue. To our knowledge, this is the first case report of lymphomatous growth in mediastinal lipomatosis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Levitt LJ, Aisenberg AC, Harris NL, Linggood RM, Poppema S. Primary non-Hodgkin’s lymphoma of the mediastinum. Cancer 1982;50:2486–92.

    Article  PubMed  CAS  Google Scholar 

  2. Trump DL, Mann RB. Diffuse large cell and undifferentiated lymphomas with prominent mediastinal involvement. Cancer 1982;50:277–82.

    Article  PubMed  CAS  Google Scholar 

  3. Jaffe ES. World Health Organization: pathology and genetics of tumours of haematopoietic and lymphoid tissues. Lyon Oxford, IARC Press; Oxford University Press, 2001.

  4. Armitage JO, Weisenburger DD. New approach to classifying non-Hodgkin’s lymphomas: clinical features of the major histologic subtypes. Non-hodgkin’s lymphoma classification project. J Clin Oncol 1998;16:2780–95.

    PubMed  CAS  Google Scholar 

  5. Addis BJ, Isaacson PG. Large cell lymphoma of the mediastinum: a B-cell tumour of probable thymic origin. Histopathology 1986;10:379–90.

    Article  PubMed  CAS  Google Scholar 

  6. Jacobson JO, et al. Mediastinal large cell lymphoma. An uncommon subset of adult lymphoma curable with combined modality therapy. Cancer 1988;62:1893–98.

    Article  PubMed  CAS  Google Scholar 

  7. Tateishi U, et al. Primary mediastinal lymphoma: characteristic features of the various histological subtypes on CT. J Comput Assist Tomogr 2004;28:782–9.

    Article  PubMed  Google Scholar 

  8. Gaerte SC, Meyer CA, Winer-Muram HT, Tarver RD, Conces DJ. Fat-containing lesions of the chest. Radiographics 2002;22:S61–78.

    PubMed  Google Scholar 

  9. Klimstra DS, Moran CA, Perino G, Koss MN, Rosai J. Liposarcoma of the anterior mediastinum and thymus. A clinicopathologic study of 28 cases. Am J Surg Pathol 1995;19:782–91.

    Article  PubMed  CAS  Google Scholar 

  10. Schweitzer DL, Aguam AS. Primary liposarcoma of the mediastinum. Report of a case and review of the literature. J Thorac Cardiovasc Surg 1977;74:83–97.

    PubMed  CAS  Google Scholar 

  11. Grewal RG, Prager K, Austin JH, Rotterdam H. Long term survival in non-encapsulated primary liposarcoma of the mediastinum. Thorax 1993;48:1276–77.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Internal Medicine, Division of Pulmonary Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Rd, Taipei, 100, Taiwan

    C. T. Huang, J. Y. Shih & P. C. Yang

  2. Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan

    W. C. Huang

Authors
  1. C. T. Huang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. W. C. Huang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. Y. Shih
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. P. C. Yang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to J. Y. Shih.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Huang, C.T., Huang, W.C., Shih, J.Y. et al. Primary mediastinal large B-cell lymphoma mimicking liposarcoma. Med Oncol 25, 284–286 (2008). https://doi.org/10.1007/s12032-007-9032-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12032-007-9032-0

Keywords

Search

Navigation