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Synthesis and Insecticidal Activity of New 4-Hydroxy-2H-1-benzopyran-2-one Derivatives

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Abstract

Several stable and storable anticoagulant rodenticides involving both merits of acute and chronic rodenticides have been synthesized (Holbrook et al. in Arch Intern Med 165:1095–1106, 2005; Baglin et al. in Br J Haematol 132:277–285, 2006). The structures of synthesized compounds were confirmed by IR, 1H NMR. The compounds were also evaluated for their anticoagulant and acute biologic activity (Lipton et al., JAMA 252:3004–3005, 3).

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Authors and Affiliations

  1. Department of Chemistry, Northeastern University, Shenyang City, 110004, People’s Republic of China

    Meijing Wang, Feng Chen, Jian Guan & Jing Zhao

  2. Jialong Naturelite Pharmaceutical R&D Co., Ltd., Anshan City, Liaoning Province, 114014, People’s Republic of China

    Jiufu Zhang

  3. Department of Organic Chemistry, Myongji University, Yongin, 449728, South Korea

    Renhe Zhao

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  1. Meijing Wang
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  2. Feng Chen
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  3. Jian Guan
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  4. Jing Zhao
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  5. Jiufu Zhang
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  6. Renhe Zhao
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Correspondence to Meijing Wang.

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Wang, M., Chen, F., Guan, J. et al. Synthesis and Insecticidal Activity of New 4-Hydroxy-2H-1-benzopyran-2-one Derivatives. Appl Biochem Biotechnol 159, 768–777 (2009). https://doi.org/10.1007/s12010-009-8619-7

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  • DOI: https://doi.org/10.1007/s12010-009-8619-7

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