ABSTRACT
BACKGROUND
Hospital readmission within thirty days is common among Medicare beneficiaries, but the relationship between rehospitalization and subsequent mortality in older adults is not known.
OBJECTIVE
To compare one-year mortality rates among community-dwelling elderly hospitalized Medicare beneficiaries who did and did not experience early hospital readmission (within 30 days), and to estimate the odds of one-year mortality associated with early hospital readmission and with other patient characteristics.
DESIGN AND PARTICIPANTS
A cohort study of 2133 hospitalized community-dwelling Medicare beneficiaries older than 64 years, who participated in the nationally representative Cost and Use Medicare Current Beneficiary Survey between 2001 and 2004, with follow-up through 2006.
MAIN MEASURE
One-year mortality after index hospitalization discharge.
KEY RESULTS
Three hundred and four (13.7 %) hospitalized beneficiaries had an early hospital readmission. Those with early readmission had higher one-year mortality (38.7 %) than patients who were not readmitted (12.1 %; p < 0.001). Early readmission remained independently associated with mortality after adjustment for sociodemographic factors, health and functional status, medical comorbidity, and index hospitalization-related characteristics [HR (95 % CI) 2.97 (2.24-3.92)]. Other patient characteristics independently associated with mortality included age [1.03 (1.02-1.05) per year], low income [1.39 (1.04-1.86)], limited self-rated health [1.60 (1.20-2.14)], two or more recent hospitalizations [1.47 (1.01-2.15)], mobility difficulty [1.51 (1.03-2.20)], being underweight [1.62 (1.14-2.31)], and several comorbid conditions, including chronic lung disease, cancer, renal failure, and weight loss. Hospitalization-related factors independently associated with mortality included longer length of stay, discharge to a skilled nursing facility for post-acute care, and primary diagnoses of infections, cancer, acute myocardial infarction, and heart failure.
CONCLUSIONS
Among community-dwelling older adults, early hospital readmission is a marker for notably increased risk of one-year mortality. Providers, patients, and families all might respond profitably to an early readmission by reviewing treatment plans and goals of care.
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REFERENCES
Jencks SF, Williams MV, Coleman EA. Rehospitalizations among patients in the Medicare fee-for-service program. N Engl J Med. 2009;360(14):1418–1428.
Hasan O, Meltzer DO, Shaykevich SA, et al. Hospital readmission in general medicine patients: a prediction model. J Gen Intern Med. 2010;25(3):211–219.
van Walraven C, Dhalla IA, Bell C, et al. Derivation and validation of an index to predict early death or unplanned readmission after discharge from hospital to the community. CMAJ. 2010;182(6):551–557.
Marcantonio ER, McKean S, Goldfinger M, Kleefield S, Yurkofsky M, Brennan TA. Factors associated with unplanned hospital readmission among patients 65years of age and older in a Medicare managed care plan. Am J Med. 1999;107(1):13–17.
Reed RL, Pearlman RA, Buchner DM. Risk factors for early unplanned hospital readmission in the elderly. J Gen Intern Med. 1991;6(3):223–228.
Silverstein MD, Qin H, Mercer SQ, Fong J, Haydar Z. Risk factors for 30-day hospital readmission in patients >/=65 years of age. Bayl Univ Med Cent Proc. 2008;21(4):363–372.
Ross JS, Mulvey GK, Stauffer B, et al. Statistical models and patient predictors of readmission for heart failure: a systematic review. Arch Intern Med. 2008;168(13):1371–1386.
Bravata DM, Ho SY, Meehan TP, Brass LM, Concato J. Readmission and death after hospitalization for acute ischemic stroke: 5-year follow-up in the medicare population. Stroke. 2007;38(6):1899–1904.
Bahadori K, FitzGerald JM, Levy RD, Fera T, Swiston J. Risk factors and outcomes associated with chronic obstructive pulmonary disease exacerbations requiring hospitalization. Can Respir J. 2009;16(4):e43–e49.
Creditor MC. Hazards of hospitalization of the elderly. Ann Intern Med. 1993;118(3):219–223.
Walter LC, Brand RJ, Counsell SR, et al. Development and validation of a prognostic index for 1-year mortality in older adults after hospitalization. JAMA. 2001;285(23):2987–2994.
Center for Medicare and Medicaid Services. Technical Documentation for the Medicare Current Beneficiary Survey. Medicare Current Beneficiary Survey Data Tables. 2003.
Elixhauser A, Steiner C, Harris D, Coffey RM. Comorbidity measures for use with administrative data. Med Care. 1998;36(1):8–27.
Elixhauser A, Steiner C, Palmer L. Clinical Classifications Software (CCS), 2012. U.S. Agency for Healthcare Research and Quality. Available: http://www.hcup-us.ahrq.gov/toolssoftware/ccs/ccs.jsp Accessed on May 12, 2012.
Ciol MA, Hoffman JM, Dudgeon BJ, Shumway-Cook A, Yorkston KM, Chan L. Understanding the use of weights in the analysis of data from multistage surveys. Arch Phys Med Rehabil. 2006;87(2):299–303.
Studenski S, Perera S, Patel K, et al. Gait speed and survival in older adults. JAMA. 2011;305(1):50–58.
Lee SJ, Moody-Ayers SY, Landefeld CS, et al. The relationship between self-rated health and mortality in older black and white Americans. J Am Geriatr Soc. 2007;55(10):1624–1629.
Landi F, Onder G, Gambassi G, Pedone C, Carbonin P, Bernabei R. Body mass index and mortality among hospitalized patients. Arch Intern Med. 2000;160(17):2641–2644.
McAuley P, Pittsley J, Myers J, Abella J, Froelicher VF. Fitness and fatness as mortality predictors in healthy older men: the veterans exercise testing study. J Gerontol A Biol Sci Med Sci. 2009;64(6):695–699.
Arbaje AI, Wolff JL, Yu Q, Powe NR, Anderson GF, Boult C. Postdischarge environmental and socioeconomic factors and the likelihood of early hospital readmission among community-dwelling Medicare beneficiaries. Gerontologist. 2008;48(4):495–504.
Koehler BE, Richter KM, Youngblood L, et al. Reduction of 30-day postdischarge hospital readmission or emergency department (ED) visit rates in high-risk elderly medical patients through delivery of a targeted care bundle. J Hosp Med. 2009;4(4):211–218.
Jack BW, Chetty VK, Anthony D, et al. A reengineered hospital discharge program to decrease rehospitalization: a randomized trial. Ann Intern Med. 2009;150(3):178–187.
Naylor MD, Brooten D, Campbell R, et al. Comprehensive discharge planning and home follow-up of hospitalized elders: a randomized clinical trial. JAMA. 1999;281(7):613–620.
Acknowledgments
The authors would like to thank Dr Robert Arnold, MD, Department of Medicine, University of Pittsburgh for critical review. Grant support from AG032291 and the Pittsburgh Claude D. Pepper Older Americans Independence Center (P30 AG024827), National Institute on Aging. Dr Hardy receives support from a Beeson Career Development Award (AG030977). This paper was presented at the American Geriatrics Society 2010 Annual Scientific Meeting, May 13, 2010.
Conflict of Interest
Drs. Lum, Degenholtz, and Hardy declare that they do not have a conflict of interest. Dr. Studenski has consulted for Merck, Novartis, and GTX, received grant funding from Merck, and received textbook royalties from McGraw Hill.
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Lum, H.D., Studenski, S.A., Degenholtz, H.B. et al. Early Hospital Readmission is a Predictor of One-Year Mortality in Community-Dwelling Older Medicare Beneficiaries. J GEN INTERN MED 27, 1467–1474 (2012). https://doi.org/10.1007/s11606-012-2116-3
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DOI: https://doi.org/10.1007/s11606-012-2116-3