Skip to main content

Advertisement

Log in

Tuberculous lymphadenitis in patients undergoing continuous ambulatory peritoneal dialysis

  • Original Article
  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

Abstract

The aim of this study was to review the clinical features of tuberculous (TB) lymphadenitis in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). Nine cases of TB lymphadenitis were diagnosed among 910 patients over a period of 10 years. There were five men and four women with a mean age of 51 ± 15.5 years. The TB lymphadenitis involved the cervical lymph nodes in six patients, supraclavicular lymph nodes in two patients and mediastinal lymph nodes in one patient. Six patients presented with clinically enlarged lymph nodes of whom four also had fever. Three other patients were incidentally found to have enlarged lymph nodes on routine chest X-ray or ultrasound examination of the neck. Diagnosis of TB lymphadenitis was made by demonstrating caseating granulomata with or without positive acid-fast bacilli on excisional lymph node biopsy. All patients were cured with standard anti-tuberculosis drugs for 12 months. No recurrence of the TB lymphadenitis was observed after a mean follow-up of 59 ± 30 months. We conclude that TB lymphadenitis is not uncommon among patients on CAPD. A high index of suspicion is needed for early diagnosis of this condition. Prompt initiation of anti-tuberculosis treatment is associated with good prognosis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Moran J, Blumenstein M, Gurland HJ (1990) Immunodeficiencies in chronic renal failure. Contrib Nephrol 86:91–106

    PubMed  CAS  Google Scholar 

  2. Garcia-Leoni ME, Martin-Scapa C, Rodeno P, Valderrabano F, Moreno S, Bouza E (1990) High incidence of tuberculosis in renal patients. Eur J Clin Microbiol Infect Dis 9:283–285

    Article  PubMed  CAS  Google Scholar 

  3. Shohaib SA, Scrimgeour EM, Shaerya F (1999) Tuberculosis in active dialysis patients in Jeddah. Am J Nephrol 19:34–37

    Article  PubMed  CAS  Google Scholar 

  4. Lui SL, Tang S, Li FK et al (2001) Tuberculosis infection in Chinese patients on continuous ambulatory peritoneal dialysis. Am J Kidney Dis 38:1055–1060

    PubMed  CAS  Google Scholar 

  5. Malik GH, Al-Harbi A, Al-Mohaya S et al (2002) Eleven years of experience with dialysis associated tuberculosis. Clin Nephrol 58:356–362

    PubMed  CAS  Google Scholar 

  6. Golden MP, Vikram HR (2005) Extrapulmonary tuberculosis: an overview. Am Fam Physician 72:1761–1768

    PubMed  Google Scholar 

  7. Lund RJ, Koch MJ, Oldemeyer JB, Meares AJ, Dunlay RW (2000) Extrapulmonary tuberculosis in patients with end stage renal disease-two case reports and a brief review. Int Urol Nephrol 32:181–183

    Article  PubMed  CAS  Google Scholar 

  8. Chuang FR, Lee CH, Wang IK, Chen JB, Wu MS (2003) Extrapulmonmary tuberculosis in chronic hemodialysis patients. Ren Fail 25:739–746

    Article  PubMed  Google Scholar 

  9. Tarng DC, Su WJ, Huang TP (1998) PCR diagnosis on formalin-fixed, paraffin-embedded tissues with acid-fast stain and culture negativity in chronic dialysis patients of cervicomediastinal tuberculous lymphadenitis. Nephrol Dial Transplant 13:1543–1546

    Article  PubMed  CAS  Google Scholar 

  10. Munck K, Mandpe AH (2003) Mycobacterial infections of the head and neck. Otolaryngol Clin North Am 36:569–576

    Article  Google Scholar 

  11. Fang JT, Chen YC, Chang MY (2004) Ethambutol-induced optic neuritis in patients with end stage renal disease on hemodialysis: two case reports and literature review. Ren Fail 26:189–193

    Article  PubMed  Google Scholar 

Download references

Acknowledgement:

The production of this paper was supported by the Tung Wah Hospital renal research fund.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sing Leung Lui.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lui, S.L., Yip, T., Tse, K.C. et al. Tuberculous lymphadenitis in patients undergoing continuous ambulatory peritoneal dialysis. Int Urol Nephrol 39, 971–974 (2007). https://doi.org/10.1007/s11255-007-9200-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11255-007-9200-3

Keywords

Navigation