Abstract
2,6-Dimethyl-5-(phenylcarbamoyl)-4-(3-nitrophenyl)-1,4-dihydropyridine-2-carboxylate was synthesized in two steps and was characterized spectroscopically and confirmed by X-ray diffraction studies. The molecule crystallizes in the monoclinic crystal class in the spacegroup P21/c with cell parameters a = 10.5960(6) Å, b = 10.2450(7) Å, c = 19.5790(11) Å, β = 107.448(3)° and Z = 4. The 1,4-dihydropyridine ring in the structure adopts a flattened boat conformation.
Graphical Abstract
2,6-Dimethyl-5-(phenylcarbamoyl)-4-(3-nitrophenyl)-1,4-dihydropyridine-2-carboxylate was synthesized in two steps and was characterized spectroscopically and confirmed by X-ray diffraction studies. The molecule crystallizes in the monoclinic crystal class in the spacegroup P21/c with cell parameters a = 10.5960(6) Å, b = 10.2450(7) Å, c = 19.5790(11) Å, β = 107.448(3)° and Z = 4. The 1,4-dihydropyridine ring in the structure adopts a flattened boat conformation.
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Acknowledgements
The authors are thankful to Department of Chemistry, Saurashtra University, Rajkot for providing laboratory facility and DST, Government of India for financial assistance under the project SP/I2/FOO/93.
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Naveen, S., Anandalwar, S.M., Prasad, J.S. et al. Synthesis and Structural Conformation Studies of a Potent Unsymmetrical 1,4-Dihydropyridine. J Chem Crystallogr 38, 315–319 (2008). https://doi.org/10.1007/s10870-008-9314-1
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DOI: https://doi.org/10.1007/s10870-008-9314-1