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Stoichiometry, complex stability, molecular size and conformational variations of metal ion crown ether complexes subject to diffusion coefficients in nonaqueous solutions

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Abstract

Both the stoichiometry and complex stability constants of crown ether complexes with metal ions have been determined by examining gradual changes in their diffusional behavior in nonaqueous solution. Diffusion coefficients, D, were evaluated by pulsed field gradient (PFG) NMR titration experiments whilst complex stability constants were determined by nonlinear curve-fitting procedures, D versus csol., which also allow the treatment of multiple complexation equilibria (1:1 to 1:2 stoichiometries). Differences in the diffusion coefficients of the various free crown ethers with respect to their metal ion complexes indicate great sensitivity to both conformational changes and changes in molecular size upon complexation.

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Acknowledgements

Prof. Dr. H.-J. Holdt is acknowledged for providing samples of the maleonitrile crown ethers, Dr. Gunter Wolf for helpful discussions on the diffusion studies and Dr. Karel D. Klika for language correction of the manuscript.

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  1. Institut für Chemie, Universität Potsdam, P.O. Box 60 15 53, 14415, Potsdam, Germany

    Philipp Wacker & Erich Kleinpeter

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  2. Erich Kleinpeter
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Correspondence to Erich Kleinpeter.

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Wacker, P., Kleinpeter, E. Stoichiometry, complex stability, molecular size and conformational variations of metal ion crown ether complexes subject to diffusion coefficients in nonaqueous solutions. J Incl Phenom Macrocycl Chem 59, 331–339 (2007). https://doi.org/10.1007/s10847-007-9332-1

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