Abstract
Background
Methanol is a highly toxic substance used as an industrial solvent and automotive antifreeze. Human consumption of methanol may result in severe visual disturbances. Because optical coherence tomography (OCT) is very useful for evaluating retinal edema and nerve fiber swelling, we used OCT to examine a patient with methanol-induced retinal toxicity.
Case
A 37-year-old man who drank industrial alcohol (100 ml/day) for 4 days.
Observations
The retinal profiles were evaluated by OCT and fluorescein angiography during the course of treatment. OCT demonstrated peripapillary nerve fiber swelling and accumulation of intraretinal fluid in the acute phase. In the chronic phase, the retinal thickness was diffusely decreased. Steroid pulse therapy was not effective, and his visual acuity was 6/200 OD and 4/100 OS 2 years after the event.
Conclusion
OCT was very useful for evaluating the severity of the retinal edema and the temporal changes in the retinal profile. Jpn J Ophthalmol 2006;50:239–241 © Japanese Ophthalmological Society 2006
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References
CD Benton FP Calhoun (1952) ArticleTitleThe ocular effects of methyl alcohol poisoning: report of a catastrophe involving three hundred and twenty persons Trans Am Acad Ophthalmol Otolaryngol 56 875–883 Occurrence Handle13005551
JT Eells MM Henry MF Lewandowski MT Seme TG Murray (2000) ArticleTitleDevelopment and characterization of a rodent model of methanol-induced retinal and optic nerve toxicity Neurotoxicology 21 321–330 Occurrence Handle10894122 Occurrence Handle1:CAS:528:DC%2BD3cXltFSit7o%3D
PK Sodhi JL Goyal DK Mehta (2001) ArticleTitleMethanol-induced optic neuropathy: treatment with intravenous high dose steroids Int J Clin Pract 55 599–602 Occurrence Handle11770356 Occurrence Handle1:CAS:528:DC%2BD38XksFGlsQ%3D%3D
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Fujihara, M., Kikuchi, M. & Kurimoto, Y. Methanol-induced Retinal Toxicity Patient Examined by Optical Coherence Tomography. Jpn J Ophthalmol 50, 239–241 (2006). https://doi.org/10.1007/s10384-005-0311-z
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DOI: https://doi.org/10.1007/s10384-005-0311-z