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Discovery of a genome of a distant relative of chicken anemia virus reveals a new member of the genus Gyrovirus

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Abstract

A 2.4-kb phi29 polymerase amplification product from serum of a diseased chicken was cloned and sequenced. The 2383-nucleotide sequence showed about 40% identity to a representative genome of chicken anemia virus (CAV), the only member of the genus Gyrovirus, family Circoviridae. The new genome had an organization similar to that of CAV: a putative 5′ untranscribed region of about 400 nt followed by three partially overlapping open reading frames encoding VP1, VP2 and VP3 homologs. The amino acid identities between these homologs and those of CAV were 38.8%, 40.3%, and 32.2%, respectively. Based on these limited similarities, it is proposed that the newly identified virus is a member of a new species in the genus Gyrovirus. For this new species, the name Avian gyrovirus 2 (AGV2) is proposed.

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Acknowledgments

We thank Felipe Bardini Rhodenbusch (MV) of the BIOVET Company, São Paulo, Brazil, who supplied sera of chickens. Helton F. dos Santos is supported by the National Council for Scientific and Technological Development (CNPq) grant no.141809/2010-8, and Paulo M. Roehe is a CNPq 1B research fellow. This work was supported by CNPq research grant no.578436/2008-6.

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Authors and Affiliations

  1. Virology Laboratory, Microbiology Department, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul (UFRGS), Av. Sarmento Leite 500, Porto Alegre, Rio Grande do Sul (RS), CEP 90050-170, Brazil

    Franciscus A. M. Rijsewijk, Helton F. dos Santos, Ana C. Franco & Paulo M. Roehe

  2. Institute for Veterinary Research “Desidério Finamor” (IPVDF), Estrada do Conde 6000, Eldorado do Sul, Rio Grande do Sul (RS), CEP 92990-000, Brazil

    Helton F. dos Santos, Thais F. Teixeira, Samuel P. Cibulski, Ana P. M. Varela, Diogenes Dezen & Paulo M. Roehe

Authors
  1. Franciscus A. M. Rijsewijk
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  2. Helton F. dos Santos
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  3. Thais F. Teixeira
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  4. Samuel P. Cibulski
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  5. Ana P. M. Varela
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  6. Diogenes Dezen
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  7. Ana C. Franco
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  8. Paulo M. Roehe
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Corresponding author

Correspondence to Franciscus A. M. Rijsewijk.

Additional information

The reported sequence has been submitted to GenBank and has accession number HM590588.

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Rijsewijk, F.A.M., dos Santos, H.F., Teixeira, T.F. et al. Discovery of a genome of a distant relative of chicken anemia virus reveals a new member of the genus Gyrovirus . Arch Virol 156, 1097–1100 (2011). https://doi.org/10.1007/s00705-011-0971-6

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  • DOI: https://doi.org/10.1007/s00705-011-0971-6

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