Abstract
Hepatocellular adenoma is a rare, benign neoplasm that is related to the use of contraceptives or androgenicanabolic steroids. A 51-year-old man with no history of steroid use was found to have a liver tumor. Plain computed tomography showed a high-density tumor that was enhanced in the arterial phase, and the enhancement was prolonged in the delayed phase. Magnetic resonance imaging showed that the tumor was hyperintense on in- and opposed-phase T1-weighted gradient recalled echo images and hyperintense on T1-weighted spin echo images. A partial hepatic resection was performed. A histological examination revealed normal hepatocyte-like tumor cells, composed of abundant dark brown granules of Dubin-Johnson-like pigment, which stained positively for Masson-Fontana stain. The tumor was diagnosed to be a very rare hepatocellular adenoma with the deposition of Dubin-Johnson-like pigment.
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Masuda, T., Beppu, T., Ikeda, K. et al. Pigmented hepatocellular adenoma: Report of a case. Surg Today 41, 881–883 (2011). https://doi.org/10.1007/s00595-010-4344-7
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DOI: https://doi.org/10.1007/s00595-010-4344-7