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The association between prevalent neck pain and health-related quality of life: a cross-sectional analysis

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Abstract

The aim of this study was to examine the association between grades of neck pain severity and health-related quality of life (HRQoL), using a population-based, cross-sectional mailed survey. The literature suggests that physical and mental HRQoL is worse for individuals with neck pain compared to those without neck pain. However, the strength of the association varies across studies. Discrepancies in study results may be attributed to the use of different definitions and measures of neck pain and differences in the selection of covariates used as control variables in the analyses. The Saskatchewan Health and Back Pain Survey was mailed to 2,184 randomly selected Saskatchewan adults of whom 1,131 returned the questionnaire. Neck pain was measured with the Chronic Pain Questionnaire and categorized into four increasing grades of severity. We measured HRQoL with the SF-36 Health Survey and computed the physical and mental component summary scores. We built separate multiple linear regression models to examine the association between grades of neck pain and physical and mental summary scores while controlling for sociodemographic, general health and comorbidity covariates. Our crude analysis suggests that a gradient exists between the severity of neck pain and HRQoL. Compared to individuals without neck pain, those with Grades III–IV neck pain have significantly lower physical (mean difference = −13.9/100; 95% CI = −16.4, −11.3) and mental (mean difference = −10.8/100; 95% CI = −13.6, −8.1) HRQoL. Controlling for covariates greatly reduced the strength of association between neck pain and physical HRQoL and accounted for the observed association between neck pain and mental HRQoL. In the comorbidity model, the strength of association between Grades III–IV neck pain and PCS decreased by more than 50% (mean difference = −4.5/100; 95% CI = −6.9, −2.0). In the final PCS model, Grades III–IV neck pain coefficients changed only slightly from the comorbidity model (mean difference = −4.4/100; 95% CI = −6.9, −1.9). This suggests that comorbid conditions account for most of the association between neck pain and PCS score. It was concluded that prevalent neck pain is weakly associated with physical HRQoL, and that it is not associated with mental HRQoL. Our cross-sectional analysis suggests that most of the observed association between prevalent neck pain and HRQoL is attributable to comorbidities.

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Acknowledgments

We would like to thank the Chiropractors’ Association of Saskatchewan for funding the Saskatchewan Health and Back Pain Survey and Selahadin Ibrahim, Stella Chan and Amber Bielecky for their assistance with data analysis. The University of Saskatchewan Advisory Committee on Ethics in Human Experimentation approved the survey.

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Authors and Affiliations

  1. Department of Public Health Sciences, University of Toronto, Toronto, Canada

    Mana Rezai, Pierre Côté & J. David Cassidy

  2. Center of Research Expertise in Improved Disability Outcomes (CREIDO), Rehabilitation Solutions, Toronto Western Hospital, University Health Network, 399 Bathurst Street, Fell Pavillion 4-144, Toronto, ON, M5T 2S8, Canada

    Mana Rezai, Pierre Côté & J. David Cassidy

  3. Division of Health Care and Outcomes Research, University Health Network, Toronto, Canada

    Pierre Côté & J. David Cassidy

  4. Department of Public Health Sciences, School of Public Health, University of Alberta, 13-103 Clinical Sciences Building, 11350-83 Avenue, Edmonton, AB, T6G 2G3, Canada

    Linda Carroll

  5. Alberta Centre for Injury Prevention and Research, Edmonton, AB, Canada

    Linda Carroll

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  1. Mana Rezai
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  2. Pierre Côté
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  3. J. David Cassidy
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  4. Linda Carroll
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Correspondence to Mana Rezai.

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Rezai, M., Côté, P., Cassidy, J.D. et al. The association between prevalent neck pain and health-related quality of life: a cross-sectional analysis. Eur Spine J 18, 371–381 (2009). https://doi.org/10.1007/s00586-008-0823-6

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  • DOI: https://doi.org/10.1007/s00586-008-0823-6

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