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Effect of body weight support on cortical activation during gait in patients with stroke

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Abstract

Treadmill training with body weight support (BWS) was shown to improve locomotion after stroke. We investigated whether BWS affected cortical activation during gait using an optical imaging system. In six patients with subcortical stroke, BWS lowered activation in the sensorimotor cortex (SMC) as assessed by task-related changes of oxygenated hemoglobin levels (P<0.01). The changes of SMC activation correlated with those of cadence (P<0.05). Improvement of asymmetry in SMC activation also correlated with improvement of asymmetric gait (P<0.05). In five age-matched controls, BWS increased overall activation (P<0.05) but did not modify gait parameters and there was no correlation between gait parameters and SMC activation. It is suggested that BWS might improve efficacy of SMC function in patients with stroke.

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Acknowledgments

This study is supported by Funds for Medical Frontier Strategy Research and Funds for Research on Dementia and Fracture from the Ministry of Welfare, Health, and Labor in Japan, and Takeda Science Foundation. We thank Ikuo Konishi and Ichiro Oda, Technology Research Laboratory, Shimadzu Corporation, Kyoto, Japan, and Mie Arita, Bobath Memorial Hospital for technical assistance for optical imaging.

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Authors and Affiliations

  1. Neurorehabilitation Research Institute, Bobath Memorial Hospital, 1-6-5, Higashinakahama, Joto-ku, 536-0023, Osaka, Japan

    Ichiro Miyai, Mitsuo Suzuki, Megumi Hatakenaka & Kisou Kubota

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  1. Ichiro Miyai
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  2. Mitsuo Suzuki
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  3. Megumi Hatakenaka
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  4. Kisou Kubota
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Correspondence to Ichiro Miyai.

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Miyai, I., Suzuki, M., Hatakenaka, M. et al. Effect of body weight support on cortical activation during gait in patients with stroke. Exp Brain Res 169, 85–91 (2006). https://doi.org/10.1007/s00221-005-0123-x

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  • DOI: https://doi.org/10.1007/s00221-005-0123-x

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