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Arthroscopic autologous chondrocyte implantation in the ankle joint

  • Ankle
  • Published:
Knee Surgery, Sports Traumatology, Arthroscopy Aims and scope

Abstract

Purpose

Autologous chondrocyte implantation (ACI) is an established procedure in the ankle providing satisfactory results. The development of a completely arthroscopic ACI procedure in the ankle joint made the technique easier and reduced the morbidity. The purpose of this investigation was to report the clinical results of a series of patients who underwent arthroscopic ACI of the talus at a mean of 7 ± 1.2-year follow-up.

Methods

Forty-six patients (mean age 31.4 ± 7.6) affected by osteochondral lesions of the talar dome (OLT) received arthroscopic ACI between 2001 and 2006. Patients were clinically evaluated using AOFAS score pre-operatively and at 12, 36 months and at final follow-up of 87.2 ± 14.5 months.

Results

The mean pre-operative AOFAS score was 57.2 ± 14.3. At the 12-month follow-up, the mean AOFAS score was 86.8 ± 13.4 (p = 0.0005); at 36 months after surgery, the mean score was 89.5 ± 13.4 (p = 0.0005); whereas at final follow-up of 87.2 ± 14.5 months it was 92.0 ± 11.2 (p = 0.0005). There were three failures. Histological and immunohistochemical evaluations of specimens harvested from failed implants generally showed several aspects of a fibro-cartilaginous tissue associated with some aspects of cartilage tissue remodelling as indicated by the presence of type II collagen expression.

Conclusion

This study confirmed the ability of arthroscopic ACI to repair osteochondral lesions in the ankle joint with satisfactory clinical results after mid-term follow-up.

Level of evidence

IV, retrospective case series.

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Authors and Affiliations

  1. Clinical Orthopaedic and Traumatology Unit I, Rizzoli Orthopaedic Institute, via Pupilli 1, 40136, Bologna, Italy

    Sandro Giannini, Roberto Buda, Alberto Ruffilli, Marco Cavallo, Gherardo Pagliazzi, Maria Chiara Bulzamini, Deianira Luciani & Francesca Vannini

  2. Laboratory of Immunorheumatology and Tissue Regeneration, Rizzoli Orthopaedic Institute, Bologna, Italy

    Giovanna Desando

Authors
  1. Sandro Giannini
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  2. Roberto Buda
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  3. Alberto Ruffilli
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  4. Marco Cavallo
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  5. Gherardo Pagliazzi
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  6. Maria Chiara Bulzamini
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  7. Giovanna Desando
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  8. Deianira Luciani
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  9. Francesca Vannini
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Correspondence to Alberto Ruffilli.

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Giannini, S., Buda, R., Ruffilli, A. et al. Arthroscopic autologous chondrocyte implantation in the ankle joint. Knee Surg Sports Traumatol Arthrosc 22, 1311–1319 (2014). https://doi.org/10.1007/s00167-013-2640-7

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  • DOI: https://doi.org/10.1007/s00167-013-2640-7

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