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Möglichkeiten und Grenzen der Farbstofflasertherapie bei kapillären Malformationen

Potential and limitations of dye laser therapy for capillary malformations

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Zusammenfassung

Kapilläre Malformationen (Naevi flammei) werden bei unter 1 % der Neugeborenen beobachtet und können mit anderen vaskulären und nichtvaskulären Fehlbildungen vergesellschaftet sein. Sie treten überwiegend (etwa 2/3) im Kopf-Hals-Bereich auf und können sehr stigmatisierend für die Betroffenen sein. Blitzlampengepumpte gepulste Farbstofflaser stellen weiterhin die Therapie der Wahl dar und können bereits im Säuglingsalter eingesetzt werden. Bei fachgerechter Anwendung treten nur selten persistierende Nebenwirkungen durch die Lasertherapie auf. Während bei den meisten Patienten eine gute Aufhellung des Naevus flammeus durch die Lasertherapie erzielt werden kann, wird nur selten ein komplettes Verschwinden der Läsion erreicht. Daher wären neue, effektivere Therapieoptionen wünschenswert.

Abstract

Capillary malformations (port-wine stains) are observed in less than 1 % of neonates and may occur coincidentally with other vascular and nonvascular malformations. Two thirds of lesions occur in the head and neck area and may have important cosmetic and psychological implications for the patients. Treatment with flashlamp-pumped pulsed dye lasers is still the therapy of choice for capillary malformations and can be applied to infants. If the laser device is used appropriately, the rate of persistent side effects is low. Although laser treatment achieves good clearance in the majority of patients with capillary malformations, complete clearance is rare. New therapeutic options are thus urgently required.

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Einhaltung ethischer Richtlinien

Interessenkonflikt. A. Klein und U. Hohenleutner geben an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren. Alle Patienten, die über Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts zu identifizieren sind, haben hierzu ihre schriftliche Einwilligung gegeben. Im Falle von nicht mündigen Patienten liegt die Einwilligung eines Erziehungsberechtigen oder des gesetzlich bestellten Betreuers vor.

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  1. Klinik und Poliklinik für Dermatologie, Universitätsklinikum Regensburg, 93042, Regensburg, Deutschland

    A. Klein &  U. Hohenleutner

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  1. A. Klein
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  2. U. Hohenleutner
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Correspondence to U. Hohenleutner.

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Klein, A., Hohenleutner, U. Möglichkeiten und Grenzen der Farbstofflasertherapie bei kapillären Malformationen. HNO 62, 25–29 (2014). https://doi.org/10.1007/s00106-013-2804-2

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  • DOI: https://doi.org/10.1007/s00106-013-2804-2

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