Abstract
An unusual granulomatous reaction within a conventional clear cell renal cancer in a 62 year-old woman is reported. Using immunohistochemical evaluation, cells of the granuloma were CD68 (Kp1), carboxypeptidase M and CD3 positive. No signs of sarcoidosis were found in other organs. According to the few publications that mention cancer associated sarcoid-like reaction, such lesions do not influence the prognosis. Our patient is still well for a 15 months follow-up.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Marinides GN, Hajdu I, Gand RO: A unique association of renal cell carcinoma with sarcoid reaction in the kidney. Nephron 67:477–480, 1994
Ryska A, Seifert G: Adenolymphoma (Whartin’s tumor) with multiple sarcoid-like granulomas. Pathol Res Pract 195:835–839, 1999
Ludvikova M, Ryska A andDrovakova E: Focal sarcoid-like change of the thyroid gland. A possible consequence of aspiration cytology? Pathol Res Pract 198:479–482, 2002
Moder KG, Litin SC andGaffey TA: Renal cell carcinoma associated with sarcoid-like tissue reaction. Mayo Clin Proc 65:1498–1501, 1990
Bottone AC, Labarbera M, Asasourian A et al: Renal sarcoidosis coexisting with hypernephroma. Urology 41:157–159, 1993
Campbell F andDouglas-Jones AG: Sarcoid-like granulomas in primary renal cell carcinoma. Sarcoidosis 10:128–131, 1992
Lucci S, Rivolta R andFazi M: Sarcoidosis and clear cell carcinoma of the kidney: the sixth case? G Chir 23:75–78, 2002
Shigematsu H, Kurita A, Omura Y et al: Gastric cancer with sarcoid reactions in the regional lymphnodes, the stomach and the splenic parenchyma. Report of a case. Surgery TodayTokyo 29:549–552, 1999
Kamiyoshihara M, Hirai T andKawashima O: Sarcoid reactions in primary pulmonary carcinoma. Report of seven cases. Oncology Reports 5:177–180, 1998
Bassler K andBirke F: Histopathology of tumor associated sarcoid-like stromal reaction in breast cancer. An analysis of 5 cases with immunohistochemical investigation. Virchows Arch A Pathol Anat Histopathol 412:231–239, 1988
Rayson D, Burch PA andRichardson RL: Sarcoidosis and testicular carcinoma. Cancer 83:337–343, 1998
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kovacs, J., Varga, A., Bessenyei, M. et al. Renal cell cancer associated with sarcoid-like reaction. Pathol. Oncol. Res. 10, 169–171 (2004). https://doi.org/10.1007/BF03033747
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF03033747