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Antifungal activity of venenatine, an indole alkaloid isolated fromAlstonia venenata

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Abstract

The indole alkaloid venenatine exhibited antifungal activity against some plant pathogenic and saprophytic fungi. Venenatine in an aqueous acetic acid solution inhibited spore germination of all the 10 tested fungi;Fusarium udum, Alternaria brassicicola, Ustilago cynodontis andAspergillus flavus showed an especially high sensitivity towards this compound, exhibiting germination levels below 10%. The spore germination and colony development of the parasitic fungusErysiphe pisi, which causes powdery mildew in pea (Pisum sativum), on excised leaves of pea was also significantly affected. Pre-inoculation rather than post inoculation treatment of the leaves was more inhibitory against spore germination and colony development.

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References

  • Asthana A., Chandra B., Dikshit A., Dixit S.N.: Volatile fungitoxicants from leaves of some higher plants againstHelmintho-sporum oryzae.Z. Pflanzenkrankh. Pflanzensch 89, 475–479 (1982).

    Google Scholar 

  • Atta-ur-Rahman, Nasreen A., Akhtar F., Shekhani M.S., Clardy J., Parvez M., Choudhuri M.I.: Antifungal diterpenoid alkaloids fromDelphinium denudatum.J. Nat. Prod. 60, 474–477 (1982).

    Google Scholar 

  • Bhattacharya S.K., Ray A.B., Dutta S.C.: Psychopharmacological investigations of 4-methoxyindole alkaloids ofAlstonia venenata.Planta Med. 27, 164–170 (1975).

    PubMed  Google Scholar 

  • Carver T.L.W., Adaigbe M.E.: Effects of host genotype, leaf age and position and incubation humidity on germination and germling developing byErysiphe graminis f.sp.avenae.Mycol. Res. 94, 18–26 (1990).

    Google Scholar 

  • Chakravarty D.K., Pariya S.N.: Inhibition of phytopathogenic fungi in some Indian medicinal plant extracts.Z. Pflanzenkrankh. Pflanzensch. 84, 221–233 (1977).

    Google Scholar 

  • Chaturvedi R., Dikshit A., Dixit S.N.:Adenocalymma allicea; a new source of a natura fungi toxicant.Trop. Agric. 64, 318–322 (1987).

    CAS  Google Scholar 

  • Govindachari T.R., Viswanathan N., Rai B.R., Savitri T.S.: Chemical constituents ofAlstonia venenata R. Br.Tetrahedron 21, 2951–2956 (1965).

    Article  PubMed  CAS  Google Scholar 

  • Kobayshi K., Nishino H., Fukushima M., Tomita H.: Antifungal activity of pisiferic acid derivatives against the rice blast fungus.Phytochemistry 26, 3175–3179 (1987).

    Article  Google Scholar 

  • Lyon G.D., Beglinski T., Newton A.C.: Novel disease control compounds: the potential to ‘immunize’ plants against infection.Plant Pathol. 44, 407–427 (1995).

    Article  CAS  Google Scholar 

  • Mailllard M., Gupta M.P., Hostetmann K.: A new antifungal prenylated flavonone fromErythrina berteroana Planta Med. 53, 563–564 (1987).

    Article  Google Scholar 

  • Prithiviraj B., Khistae S., Ram D., Singh U.P.: Effect of methanol extract ofAegle marmalos leaves on mycelial growth and sclerotium formation ofSclerotium rolfsii.Internat. J. Pharmacogn. 36, 148–150 (1996).

    Google Scholar 

  • Prithiviraj B., Manickam M., Singh U.P., Ray A.B.: Antifungal activity of anacardic acid, a naturally occurring derivative of salicylic acid.Can. J. Bot. 75, 207–211 (1997).

    Article  CAS  Google Scholar 

  • Prithiviraj B., Singh U.P., Manickam M., Srivastava J.S., Ray A.B.: Antifungal activity of bergenin, a constituent ofFlueggea microcarpa.Plant Pathol. 46, 224–228 (1997).

    Article  CAS  Google Scholar 

  • Prithiviraj B., Singh U.P., Singh K.P., Plank-Schumacher K.: Full evaluation of ajoene, as constituent of garlic (Allium sativum) and neemazal, a product of neem (Azadirachta indica) for the control of powdery mildew (Erysiphe pisi) of pea (Pisum sativum).Z. Pflanzenkrankh. Pflanzensch. 105, 274–278 (1998).

    CAS  Google Scholar 

  • Ray A.B., Chatterjee A.: Further studies on the major alkaloids of the stem-bark ofAlstonia venenata R.Br. Structure and stereochemistry of alstovenine and its congeners.J. Ind. Chem. Soc. 41, 638 (1964).

    CAS  Google Scholar 

  • Reimers F., Smolka S.E., Werres S., Plank-Schumacher K., Wagner K.G.: Effect of ajoene, a compound derived fromAllium sativum, on phytopathogenic and epiphytic micro-organisms.Z. Pflanzenkrankh. Pflanzensch. 100, 622–633 (1993).

    CAS  Google Scholar 

  • Sarma B.K., Pandey V.B., Mishra G.D., Singh U.P.: Antifungal activity of berberine iodide, a constituent ofFumaria indica.Folia Microbiol. 44, 164–166 (1999).

    Article  CAS  Google Scholar 

  • Singh S.K., Sarma B.K., Srivastava J.S., Singh U.P., Ray A.B.: Antifungal activity of Δ3-alstovenine, a plant alkaloid isolated fromAlstonia venenata.Folia Microbiol. 44, 510–512 (1999).

    Article  CAS  Google Scholar 

  • Singh U.P., Chauhan V.B., Wagner K.G., Kumar A.: Effect of ajoene, a compound derived from garlic (Allium sativum L.) ofPhytophthora drechsleri f.sp.cajani.Mycologia,84, 105–108 (1992).

    Article  CAS  Google Scholar 

  • Singh U.P., Pandey V.B., Singh R.N., Singh R.D.N.: Antifungal activity of some new flavonones and flavone glycosides ofEschinops echinatus.Can. J. Bot. 66, 1901–1903 (1988).

    CAS  Google Scholar 

  • Singh U.P., Pandey V.N., Wagner K.G., Singh K.P.: Antifungal activity of ajoene, a constituent of garlic (Allium sativum).Can. J. Bot. 68, 1354–1356 (1990).

    Google Scholar 

  • Singh U.P., Prithiviraj B., Wagner K.G., Plank-Schumacher K.: Effect of ajoene, a constituent of garlic (Allium sativum), on powdery mildew (Erysiphe pisi) of pea (Pisum sativum).Z. Pflanzenkrankh. Pflanzensch. 102, 399–406 (1995).

    CAS  Google Scholar 

  • Singh U.P., Singh H.B., Chauhan V.B.: Effect of some fungicides, plant extracts and oil on inoculum density of different nodal leaves of powdery mildew of pea.J. Phytopathol. 91, 20–26 (1984).

    Google Scholar 

  • Singh U.P., Singh K.P., Tripathi V.K., Pandey V.B.: Antifungal activity of some naturally occurring plant alkaloids.Internat. J. Trop. Plant Dis. 12, 209–212 (1994).

    Google Scholar 

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Singh, U.P., Sarma, B.K., Mishra, P.K. et al. Antifungal activity of venenatine, an indole alkaloid isolated fromAlstonia venenata . Folia Microbiol 45, 173–176 (2000). https://doi.org/10.1007/BF02817419

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